Management of Prosthetic Tricuspid Valve Thrombosis with Streptokinase

Despite improvements in the design of mechanical prosthetic heart valves and regular use of anticoagulation, prosthetic heart valve thrombosis remain the most dreadful complication associated with high mortality. Surgical thrombectomy or valvereplacement is used as a conventional therapy. Medical thrombolysis, on the other hand, is a therapy choice. Present case is of a 26-year old female with Ebstein's irregularity who effectively endured tricuspid prosthetic valve thrombolysis usingintravenous Streptokinase (SK). The outcome of our patient supports that SK can be an adequate therapeutic option for thrombolysis of tricuspid Prosthetic Valve Thrombosis (PVT) in children and adolescents.