受谐波热负荷影响的有限生物组织的修正摩尔-吉布森-汤普森-潘尼斯生物传热模型

IF 2.1 4区 材料科学 Q2 MATERIALS SCIENCE, CHARACTERIZATION & TESTING
Sami F. Megahid, Ahmed E. Abouelregal, Hamid M. Sedighi
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引用次数: 0

摘要

医学家经常使用彭氏生物热方程作为计算工具,以理解热能在活体组织内分散的复杂动态。该方程具有显著的实用性,在治疗干预领域,尤其是热疗领域,具有极其重要的意义。这项技术的应用极大地促进了治疗方案的优化和人体重要解剖区域温度水平的保持。为了确保治疗的有效性,维护患者的最大福祉,必须对受到热刺激的组织的热反应进行细致的监测。本研究采用摩尔-吉布森-汤普森(MGT)方程,介绍了彭斯方程的数学公式,专门用于捕捉皮肤组织复杂结构中发生的生物热传导现象。该模型能够准确预测人体皮肤对温度变化的热反应。该模型的关键区别在于加入了时间延迟的概念。加入这一概念的目的是尽量减少热能在生物组织内的快速传播,最终限制热能以有限的速度扩散。所提出的模型用于描述受到谐波热刺激的细长、受约束的皮肤组织层中热传递的复杂性。计算结果借助示意图展示,有效地突出了模型参数对材料内部温度和变形分布的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Modified Moore–Gibson–Thompson Pennes’ bioheat transfer model for a finite biological tissue subjected to harmonic thermal loading

Modified Moore–Gibson–Thompson Pennes’ bioheat transfer model for a finite biological tissue subjected to harmonic thermal loading

Medical scientists frequently employ the Pennes bioheat equation as a computational tool to comprehend the intricate dynamics of thermal energy dispersion within living tissues. This equation, endowed with pronounced utility, finds paramount significance in the realm of therapeutic interventions, notably hyperthermia, wherein regulated elevation of tissue temperatures is administered for multifarious medical objectives. The utilization of this technology significantly enhances the optimization of treatment protocols and the preservation of temperature levels within crucial anatomical regions of the human body. To ensure the effectiveness of therapies and to uphold the utmost welfare of patients, meticulous monitoring of the thermal response of tissues subjected to thermal stimuli becomes imperative. This study introduces a mathematical formulation of the Pennes equation, specifically tailored for capturing the biothermal conduction phenomena transpiring in the intricate structure of skin tissue by employing the Moore–Gibson–Thompson (MGT) equation. This model enables accurate predictions of the thermal response of human skin to temperature variations. The key differentiating factor of this model is the incorporation of the concept of time delay. This inclusion serves the purpose of minimizing the rapid propagation of thermal energy within biological tissues, ultimately restricting its diffusion at limited rates. The proposed model is employed to characterize the intricacies of heat transfer in a slender, constrained stratum of skin tissue that is subject to a harmonic thermal stimulus. The computational outcomes are presented with the aid of illustrative figures, effectively highlighting the impact of model parameters on the temperature and deformation distributions within the material.

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来源期刊
Mechanics of Time-Dependent Materials
Mechanics of Time-Dependent Materials 工程技术-材料科学:表征与测试
CiteScore
4.90
自引率
8.00%
发文量
47
审稿时长
>12 weeks
期刊介绍: Mechanics of Time-Dependent Materials accepts contributions dealing with the time-dependent mechanical properties of solid polymers, metals, ceramics, concrete, wood, or their composites. It is recognized that certain materials can be in the melt state as function of temperature and/or pressure. Contributions concerned with fundamental issues relating to processing and melt-to-solid transition behaviour are welcome, as are contributions addressing time-dependent failure and fracture phenomena. Manuscripts addressing environmental issues will be considered if they relate to time-dependent mechanical properties. The journal promotes the transfer of knowledge between various disciplines that deal with the properties of time-dependent solid materials but approach these from different angles. Among these disciplines are: Mechanical Engineering, Aerospace Engineering, Chemical Engineering, Rheology, Materials Science, Polymer Physics, Design, and others.
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