宫颈正常上皮朗格汉斯细胞的免疫组化特征及分布。

Basic and applied histochemistry Pub Date : 1989-01-01
C Di Loreto, C A Beltrami, M De Nictolis, R Casaccia, D Stramazzotti
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引用次数: 0

摘要

使用免疫组织学方法,在32名年龄在25岁至68岁之间的妇女的正常宫颈组织中发现朗格汉斯细胞(LCs)。宫颈化生上皮和原生鳞状上皮中均检测到LCs;Dako-LC和OKDR抗体阳性,位于基底-上基底上皮层的细胞也呈okt6阳性。LCs的密度在月经周期的增殖期较高。对间质和鳞状上皮中淋巴细胞的调查显示,t淋巴细胞群主要被鉴定为t细胞毒性/抑制细胞,有时与lc接触。讨论了这些发现的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunohistochemical characterization and distribution of Langerhans cells in normal epithelium of the uterine cervix.

Langerhans cells (LCs) were shown up in normal cervical tissue obtained from 32 women whose age ranged from 25 to 68 years, using immunohistological methods. LCs were detected in metaplastic and native squamous epithelium of the cervix; they were positive to Dako-LC and OKDR antibodies and those located in the basal-suprabasal epithelial layers were also OKT6-positive. The density of the LCs was higher during the proliferative phase of the menstrual cycle. The investigation into the lymphocytes present in the stroma and in the squamous epithelium showed a population of T-lymphocytes identified as predominantly T-cytotoxic/suppressor cells, sometimes in contact with LCs. The significance of these findings is discussed.

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