探索非小细胞肺癌 MR 引导放疗的优势与挑战:谁是最佳候选者?

IF 2.6 3区 医学 Q3 ONCOLOGY
Trudy C. Wu , Lauren M. Smith , David Woolf , Corinne Faivre-Finn , Percy Lee
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引用次数: 0

摘要

过去十年来,随着现代 RT 和外科技术、系统疗法以及 RT 适应症的不断扩大,肺部放射治疗(RT)的发展日新月异。迄今为止,已有两台磁共振引导 RT(MRgRT)设备投入商业使用,其中一台使用 0.35T 磁体,另一台使用 1.5T 磁体,还有更多系统正在研发中。MRgRT 具有明显的优势,如实时目标跟踪、减少边缘和台上治疗适应性,这可能有助于克服与胸部 RT 相关的许多常见挑战。然而,使用 MRI 进行图像引导和当前的 MRgRT 设备也有其内在的局限性。在这篇综述文章中,我们将讨论迄今为止的临床经验、肺部 MRgRT 的优势、挑战和未来发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the Advantages and Challenges of MR-Guided Radiotherapy in Non–Small-Cell Lung Cancer: Who are the Optimal Candidates?

The landscape of lung radiotherapy (RT) has rapidly evolved over the past decade with modern RT and surgical techniques, systemic therapies, and expanding indications for RT. To date, 2 MRI-guided RT (MRgRT) units, 1 using a 0.35T magnet and 1 using a 1.5T magnet, are available for commercial use with more systems in the pipeline. MRgRT offers distinct advantages such as real-time target tracking, margin reduction, and on-table treatment adaptation, which may help overcome many of the common challenges associated with thoracic RT. Nonetheless, the use of MRI for image guidance and the current MRgRT units also have intrinsic limitations. In this review article, we will discuss clinical experiences to date, advantages, challenges, and future directions of MRgRT to the lung.

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来源期刊
CiteScore
5.80
自引率
0.00%
发文量
48
审稿时长
>12 weeks
期刊介绍: Each issue of Seminars in Radiation Oncology is compiled by a guest editor to address a specific topic in the specialty, presenting definitive information on areas of rapid change and development. A significant number of articles report new scientific information. Topics covered include tumor biology, diagnosis, medical and surgical management of the patient, and new technologies.
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