不受控制的废物场所空气传播致癌物风险的筛选水平评估。

T F Wolfinger
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引用次数: 11

摘要

本报告提出了对不受控制的废物场所排放的空气引起的癌症风险一般水平的筛查水平估计。随机选择25个国家重点清单站点,并根据最大暴露个体风险(MEI风险)、平均个体风险(AEI风险)和人群发病率估算每个站点的空气传播癌症风险。这些估计是根据环境保护局人体暴露模型,根据对现场排放的速率和毒性的假设得出的。MEI风险范围从4 × 10(-9)到1 × 10(-6),平均约为5 × 10(-7)。居住在4英里范围内的人的AEI风险平均约为10(-8),居住在较远距离的人的AEI风险显著下降。所有站点的人口发病率都很低,在站点周围60英里范围内,预计癌症病例数为2 × 10(-4)至1 × 10(-2)。由于这种类型的分析和潜在的研究假设的不确定性,这些结果必须谨慎看待。尽管如此,可以从分析中得出一些初步结论,主要是在大多数情况下,来自不受控制的废物场址的空气传播癌症风险可能很小,最令人担忧的是最大程度受照射的个人,而不是受照射人群中预期的癌症病例数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening-level assessment of airborne carcinogen risks from uncontrolled waste sites.

This report presents screening-level estimates of the general level of cancer risks arising from air emission from uncontrolled waste sites. Twenty-five National Priorities List sites were chosen randomly and airborne cancer risks estimated for each site in terms of risk to the maximally exposed individual (MEI risk), average individual risk (AEI risk), and population incidence. The estimates were developed using the EPA Human Exposure Model using assumptions on the rate and toxicity of site emissions. MEI risks ranged from 4 X 10(-9) to 1 X 10(-6) with an average of about 5 X 10(-7). AEI risks for individuals residing within four miles of the sites average about 10(-8), declining significantly for individuals residing at longer distances. Population incidence was low at all sites ranging from 2 X 10(-4) to 1 X 10(-2) cancer cases expected within 60 miles of the sites. Due to the uncertainties in this type of analysis and the underlying study assumptions, these results must be viewed with caution. Nonetheless, some preliminary conclusions can be drawn from the analysis, principally that airborne cancer risks from uncontrolled waste sites are likely to be small in most cases, with the greatest concern being maximally exposed individuals rather than the number of cancer cases expected in the exposed population.

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