利用 KinExA 和表面等离子体共振确定高亲和力抗体的亲和力

IF 5.6 2区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

mAbs Pub Date : 2023-12-13 DOI:10.1080/19420862.2023.2291209

M. Frank Erasmus, Molly Dovner, Fortunato Ferrara, Sara D’Angelo, André A. Teixeira, Camila Leal-Lopes, Laura Spector, Elizabeth Hopkins, Andrew R. M. Bradbury

引用次数: 0

摘要

治疗性单克隆抗体是发展最快的药物类别之一，准确、高效的亲和力测量技术对于治疗性单克隆抗体的生物物理特性至关重要。表面塑料…

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Determining the affinities of high-affinity antibodies using KinExA and surface plasmon resonance

Accurate and efficient affinity measurement techniques are essential for the biophysical characterization of therapeutic monoclonal antibodies, one of the fastest growing drug classes. Surface plas...

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来源期刊

mAbs 工程技术-仪器仪表

CiteScore

10.70

自引率

11.30%

发文量

审稿时长

6-12 weeks

期刊介绍： mAbs is a multi-disciplinary journal dedicated to the art and science of antibody research and development. The journal has a strong scientific and medical focus, but also strives to serve a broader readership. The articles are thus of interest to scientists, clinical researchers, and physicians, as well as the wider mAb community, including our readers involved in technology transfer, legal issues, investment, strategic planning and the regulation of therapeutics.