确定患有妇科肿瘤的妇女体内中性粒细胞胞外捕获器的临床意义

Q3 Medicine

Obstetrics, Gynecology and Reproduction Pub Date : 2023-12-04 DOI:10.17749/2313-7347/ob.gyn.rep.2023.447

Z. Aslanova, J. Khizroeva, A. Solopova, V. A. Solodkiy, A. Vorobev, D. Blinov, M. D. Aslanova, I. K. Nakaidze, J.-С. Gris, I. Elalamy, A. Makatsariya

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引用次数: 0

摘要

中性粒细胞胞外陷阱(net)的形成在2004年首次被描述为一种以前未知的中性粒细胞对抗微生物的策略，已经引起了研究界越来越大的兴趣。NETs在炎症和感染中发挥关键作用，发挥诸如脱颗粒、吞噬和活性氧(ROS)产生等效应功能。net在防御全身性感染方面起着至关重要的作用，此外还参与非传染性疾病，如炎症、自身免疫性疾病和癌症。

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Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms

The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as degranulation, phagocytosis as well as production of reactive oxygen species (ROS). NETs play a crucial role in defense against systemic infections additionally participating in non-infectious diseases such as inflammation, autoimmune disorders, and cancer.

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来源期刊

Obstetrics, Gynecology and Reproduction Medicine-Embryology

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

12 weeks