Investigation of the level of agreement between bone mineral density and trabecular bone score regarding gender, age and body mass index

Introduction: Increasing and maintaining bone density can play a role in preventing osteoporosis, as changes in the trabecular bone score (TBS) and bone mineral density (BMD) affect bone density, especially in the spine. Objectives: The present study aimed to determine the level of agreement between TBS and BMD in patients with osteoporosis and also to investigate the relationship between these two indices with body mass index (BMI). Patients and Methods: Data were collected from 843 patients, referred to the densitometry department of Resalat hospital. BMD and TBS were measured in the subjects to determine the risk of osteoporosis. The results of BMD were measured based on T-score level. The patients’ individual and clinical characteristics were also recorded and factors influencing the prognosis of density changes were evaluated. Moreover, the effect of BMI was investigated in this study. Results: The mean age of patients was 55.5 years. The kappa coefficient and Spearman’s correlation coefficient of BMD and TBS were 0.004 and -0.015, respectively. There was a significant correlation between BMI and BMD in men. The kappa coefficient gradually increased from normal bone density to osteoporosis. There was a significant negative correlation between BMI and BMD, while a significant positive correlation between height and BMD in women was existed. On the other hand, a significant negative correlation between weight and BMD was detected accordingly. Conclusion: According to the results of our study, there is no agreement between BMD and TBS.