5-/12 脂氧合酶-BLT2 级联反应诱导 c-Myc 表达升高，从而介导 KRAS 突变结直肠癌细胞的增殖和迁移

IF 2.5 2区生物学 Q3 CELL BIOLOGY

Animal Cells and Systems Pub Date : 2023-12-11 DOI:10.1080/19768354.2023.2290031

Jaein Park, Jae-Hyun Jang, Jun-Dong Wei, Jae-Hong Kim

{"title":"5-/12 脂氧合酶-BLT2 级联反应诱导 c-Myc 表达升高，从而介导 KRAS 突变结直肠癌细胞的增殖和迁移","authors":"Jaein Park, Jae-Hyun Jang, Jun-Dong Wei, Jae-Hong Kim","doi":"10.1080/19768354.2023.2290031","DOIUrl":null,"url":null,"abstract":"Colorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"58 1","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The 5-/12-lipoxygenase-BLT2 cascade induces elevated expression of c-Myc, thus mediating the proliferation and migration of KRAS mutant colorectal cancer cells\",\"authors\":\"Jaein Park, Jae-Hyun Jang, Jun-Dong Wei, Jae-Hong Kim\",\"doi\":\"10.1080/19768354.2023.2290031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Colorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the...\",\"PeriodicalId\":7804,\"journal\":{\"name\":\"Animal Cells and Systems\",\"volume\":\"58 1\",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2023-12-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Animal Cells and Systems\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1080/19768354.2023.2290031\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Animal Cells and Systems","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/19768354.2023.2290031","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CELL BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

结肠直肠癌（CRC）是最常见的恶性肿瘤，也是全球癌症相关死亡的主要原因之一。癌基因 KRAS 是 CRC 中常见的突变基因，在 CRC 的发生和发展过程中起着至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The 5-/12-lipoxygenase-BLT2 cascade induces elevated expression of c-Myc, thus mediating the proliferation and migration of KRAS mutant colorectal cancer cells

Colorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the...

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Animal Cells and Systems 生物-动物学

CiteScore

4.50

自引率

24.10%

发文量

审稿时长

6 months

期刊介绍： Animal Cells and Systems is the official journal of the Korean Society for Integrative Biology. This international, peer-reviewed journal publishes original papers that cover diverse aspects of biological sciences including Bioinformatics and Systems Biology, Developmental Biology, Evolution and Systematic Biology, Population Biology, & Animal Behaviour, Molecular and Cellular Biology, Neurobiology and Immunology, and Translational Medicine.