LTN1 通过 ESCRT 途径促进 RLR 降解，抑制对 RNA 病毒的免疫反应

IF 14.6 1区生物学 Q1 CELL BIOLOGY

Autophagy Pub Date : 2023-12-07 DOI:10.1080/15548627.2023.2291939

Fei Qin, Baoshan Cai, Peng Wang, Runyu Cao, Yuling Zhang, Hongling Wen, Yi Zheng, Wei Zhao, Chengjiang Gao, Bingyu Liu

引用次数: 0

摘要

免疫反应的过度激活会引发自身免疫性疾病或炎症损伤。转运所需的内体分拣复合物（ESCRT）系统可以捕获和介导免疫反应，并将其转化为免疫细胞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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LTN1 promotes RLR degradation to inhibit immune response to RNA virus through the ESCRT pathway

The excessive activation of immune responses will trigger autoimmune diseases or inflammatory injury. The endosomal sorting complexes required for transport (ESCRT) system can capture and mediate u...

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来源期刊

Autophagy 生物-细胞生物学

CiteScore

21.30

自引率

2.30%

发文量

277

审稿时长

1 months

期刊介绍： Autophagy is a peer-reviewed journal that publishes research on autophagic processes, including the lysosome/vacuole dependent degradation of intracellular material. It aims to be the premier journal in the field and covers various connections between autophagy and human health and disease, such as cancer, neurodegeneration, aging, diabetes, myopathies, and heart disease. Autophagy is interested in all experimental systems, from yeast to human. Suggestions for specialized topics are welcome. The journal accepts the following types of articles: Original research, Reviews, Technical papers, Brief Reports, Addenda, Letters to the Editor, Commentaries and Views, and Articles on science and art. Autophagy is abstracted/indexed in Adis International Ltd (Reactions Weekly), EBSCOhost (Biological Abstracts), Elsevier BV (EMBASE and Scopus), PubMed, Biological Abstracts, Science Citation Index Expanded, Web of Science, and MEDLINE.