P Hrbas, B Cerný, O S Papsuevich, G I Chipens, A Ermisch, T Barth
{"title":"[8- l -精氨酸，9-去甘氨酸酰胺]抗利尿激素的氚化。","authors":"P Hrbas, B Cerný, O S Papsuevich, G I Chipens, A Ermisch, T Barth","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Tritiated vasopressin analogue, [8-L-arginine, 9-desglycineamide]-vasopressin was prepared from its diiodo-derivative by means of catalytic reductive dehalogenation. The reaction products were purified by reversed-phase HPLC resulting in a labelled peptide with high specific radioactivity (629 TBq/mmol).</p>","PeriodicalId":11547,"journal":{"name":"Endocrinologia experimentalis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tritiation of [8-L-arginine, 9-desglycineamide] vasopressin.\",\"authors\":\"P Hrbas, B Cerný, O S Papsuevich, G I Chipens, A Ermisch, T Barth\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Tritiated vasopressin analogue, [8-L-arginine, 9-desglycineamide]-vasopressin was prepared from its diiodo-derivative by means of catalytic reductive dehalogenation. The reaction products were purified by reversed-phase HPLC resulting in a labelled peptide with high specific radioactivity (629 TBq/mmol).</p>\",\"PeriodicalId\":11547,\"journal\":{\"name\":\"Endocrinologia experimentalis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Endocrinologia experimentalis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endocrinologia experimentalis","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
以其二碘衍生物为原料，采用催化还原脱卤法制备了加压素类似物[8- l -精氨酸，9-去甘氨酸酰胺]-加压素。反应产物经反相高效液相色谱纯化得到具有高比放射性(629 TBq/mmol)的标记肽。
Tritiation of [8-L-arginine, 9-desglycineamide] vasopressin.
Tritiated vasopressin analogue, [8-L-arginine, 9-desglycineamide]-vasopressin was prepared from its diiodo-derivative by means of catalytic reductive dehalogenation. The reaction products were purified by reversed-phase HPLC resulting in a labelled peptide with high specific radioactivity (629 TBq/mmol).
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
