角膜透明度问题的数学模型

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Araújo, Adérito, Barbeiro, Sílvia, Bernardes, Rui, Morgado, Miguel, Sakić, Sunčica
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引用次数: 0

摘要

了解角膜透明的物理基础一直是物理学家、基础科学家和眼科医生感兴趣的课题。角膜清晰度的损害是世界范围内视力发病率的一个重要原因。因此,了解角膜透明度背后的机制以及角膜病变如何影响视力是至关重要的。我们使用麦克斯韦方程组来模拟光在眼组织中的传播,并使用结不连续伽辽金方法结合显式龙格-库塔方法来模拟正常和病理角膜中的光传播。我们的模拟结果表明,一些光纤直径的增加会导致后向散射的增加。因此,这些可能代表了角膜的一些物理变化,可能导致透明度的丧失和视力的发病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A mathematical model for the corneal transparency problem
Understanding the physical basis of corneal transparency has been a subject of interest amongst physicists, basic scientists and ophthalmologists. Impairment of corneal clarity is a significant cause of visual morbidity worldwide. Thus, it is essential to understand the mechanisms behind corneal transparency and how the alterations due to corneal pathologies affect vision. We use Maxwell’s equations to model light propagation in ocular tissues and a nodal discontinuous Galerkin method combined with an explicit Runge-Kutta method to simulate light propagation in normal and pathological corneas. Our simulation results illustrate that an increase in the diameter of some fibres causes an increase in backscattering. Thus, these may represent some of the physical changes in the cornea that might result in loss of transparency and visual morbidity.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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