A Detailed Investigation and Catalytic Application of Gold Nanoparticles Towards Synthesis of N & O-Heterocycles

Nanotechnology advancements, notably in catalysis, have found several uses in the fabrication of heterocyclic molecules. An abundance nanoparticle (NPs) has been successfully used in a variety of organic transformations, which prompted us to undertake concentrated efforts to cover all instances in which gold nanoparticles (Au NPs) have been used in organic transformations. The catalytic application of gold nanoparticles in organic transformation has gained considerable interest researchers owing to its physical and chemical properties. Gold nanoparticles as catalysts in organic reactions deliver robust, green, and cost-effective alternatives for the synthetic transformations of heterocyclic scaffolds. Nitrogen- and oxygen-containing heterocyclic atoms are the essential prime units existing in diverse carbon-based vibrant lives and are substantial for industrial, pharmaceutical, and agrochemicals. Our focus will be on Au NP-catalyzed reactions in synthetic transformations for the production of heterocyclic scaffolds containing nitrogen and oxygen heteroatoms documented from 2011 to 2022. From a synthetic standpoint, this review will offer the reader an intrinsic framework for selecting the optimal Au NP catalytic system of importance for the synthesis of the preferred heterocyclic scaffold.

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