氯氮平血清浓度被SARS-CoV-2疫苗破坏。

Q4 Medicine

Case Reports in Psychiatry Pub Date : 2023-11-27 eCollection Date: 2023-01-01 DOI:10.1155/2023/9914879

Xenia A K Kersting, Nicoletta Momtahen, Klaus Lieb

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引用次数: 0

摘要

本文报告了一名27岁的偏执型精神分裂症患者，他最终在氯氮平药物治疗下稳定下来。接种严重急性呼吸综合征冠状病毒2型疫苗后，血清氯氮平水平升高。众所周知，免疫反应可触发细胞因子级联反应，影响药物代谢，在氯氮平治疗的情况下，可导致严重中毒。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations.

This paper reports the case of a 27-year-old man with paranoid schizophrenia who was finally stabilized on clozapine medication. After vaccination against severe acute respiratory syndrome coronavirus 2, serum levels of clozapine increased. It is well established that immune responses can trigger cytokine cascades affecting drug metabolism, which, in the case of clozapine treatment, can lead to severe intoxication.

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来源期刊

Case Reports in Psychiatry Medicine-Psychiatry and Mental Health

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

12 weeks