角膜共聚焦显微镜识别1型糖尿病青少年结构小纤维异常和低血糖意识受损。

IF 0.6 Q4 ENDOCRINOLOGY & METABOLISM

Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2023-01-01 Epub Date: 2023-07-15 DOI:10.15605/jafes.038.02.21

Mainak Banerjee, Pradip Mukhopadhyay, Madhurima Basu, Sujoy Ghosh

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引用次数: 0

摘要

大约25-40%的1型糖尿病(T1DM)患者存在低血糖意识受损(IAH)。在此，我们报告了一例青少年T1DM和IAH，与没有IAH的T1DM青少年相比，他的角膜神经参数更差。角膜共聚焦显微镜在一种易于操作的客观无创测试中检测到的小纤维异常可能是T1DM和IAH潜在自主神经功能障碍的替代指标。

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Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia.

Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected by corneal confocal microscopy in an objective easy-to-perform non-invasive test might be a surrogate indicator of underlying autonomic dysfunction in T1DM and IAH.

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来源期刊

Journal of the ASEAN Federation of Endocrine Societies ENDOCRINOLOGY & METABOLISM-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.