猫冠状病毒和FIP的动力学:一种分区建模方法。

IF 1.9 Q2 VETERINARY SCIENCES
Veterinary Medicine International Pub Date : 2023-11-17 eCollection Date: 2023-01-01 DOI:10.1155/2023/2721907
Ayse Peker Dobie, Alper Bayrakal, Mehmet Erman Or, Ayse Humeyra Bilge
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引用次数: 0

摘要

入侵人类和非人类群体的传染性病原体的调查代表了数学生物学框架内的一个丰富的研究领域,吸引了各个学科的科学家的兴趣。在这项工作中,我们使用改进的易感-感染-易感流行病学模型研究了猫冠状病毒和猫感染性腹膜炎的地方性平衡。我们纳入了从FCoV到FIP突变的概念,以丰富我们的分析。我们建立的模型,当受到合理的参数范围,支持地方性平衡,其中FCoV群体占主导地位。为了证明在典型参数和初始条件下均衡的稳定性,我们采用了Dobie在2022年提出的SCF模型(Dobie, 2022)。我们确定平衡值位于稳定性的内域内。此外,我们展示了不安的解决方案,以加强我们的理解。值得注意的是,我们的研究结果与现有文献的定性一致,这些文献报道了流浪猫中FCoV血清阳性的患病率(Tekelioglu等人,2015年,Oğuzoğlu等人,2010年,Pratelli 2008年,Arshad等人,2004年)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamics of Feline Coronavirus and FIP: A Compartmental Modeling Approach.

The investigation of infectious agents invading human and nonhuman populations represents a rich research domain within the framework of mathematical biology, captivating the interest of scientists across various disciplines. In this work, we examine the endemic equilibrium of feline coronavirus and feline infectious peritonitis by using a modified susceptible-infected-susceptible epidemiological model. We incorporate the concept of mutations from FCoV to FIP to enrich our analysis. We establish that the model, when subjected to reasonable parameter ranges, supports an endemic equilibrium wherein the FCoV group dominates. To demonstrate the stability of the equilibria under typical parameters and initial conditions, we employ the model SCF presented by Dobie in 2022 (Dobie, 2022). We ascertain that the equilibrium values reside within the interior domains of stability. Additionally, we displayed perturbed solutions to enhance our understanding. Remarkably, our findings align qualitatively with existing literature, which reports the prevalence of seropositivity to FCoV among stray cats (Tekelioglu et al. 2015, Oğuzoğlu et al. 2010, Pratelli 2008, Arshad et al. 2004).

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来源期刊
Veterinary Medicine International
Veterinary Medicine International Veterinary-Veterinary (all)
CiteScore
3.50
自引率
3.20%
发文量
55
审稿时长
17 weeks
期刊介绍: Veterinary Medicine International is a peer-reviewed, Open Access journal that publishes original research articles and review articles in all areas of veterinary research. The journal will consider articles on the biological basis of disease, as well as diagnosis, prevention, treatment, and epidemiology.
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