伊朗南部人口唾液腺肿瘤流行病学特征:405例回顾性研究

IF 1.8 Q3 ONCOLOGY
Journal of Cancer Epidemiology Pub Date : 2023-11-20 eCollection Date: 2023-01-01 DOI:10.1155/2023/8844535
Hamid Ghaderi, Estie Kruger, Simin Ahmadvand, Yousef Mohammadi, Bijan Khademi, Abbas Ghaderi
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引用次数: 0

摘要

目的:唾液腺肿瘤(sgt)是一种罕见而多样的肿瘤,占所有头颈部恶性肿瘤的3%至10%。我们的目标是对伊朗南部sgt进行全面的流行病学分析,并将调查结果与伊朗和世界其他地区以前的报告进行比较。方法:采用回顾性研究,在2013年4月至2021年10月期间,在伊朗设拉子观察了405名被诊断为sgt的患者。患者的人口学和临床病理特征从患者的记录中获得。采用SPSS软件进行定量和描述性数据分析。结果:良性sgt 302例(74.5%),恶性sgt 103例(25.4%)。多形性腺瘤和Warthin肿瘤是最常见的良性sgs(分别为70.5%和21.5%)。最常见的恶性sgt是粘液表皮样癌和腺样囊性癌(分别为26.2%和22.3%)。肿瘤来源与恶性程度有统计学意义(p < 0.001)。良性肿瘤多见于腮腺(p < 0.05)。良性肿瘤在年轻人群中更为常见(p = 0.006)。结论:总之,目前研究的结果与伊朗和世界其他地区以前的报告基本一致。良性肿瘤是sgt最常见的类型,腮腺是最常见的部位。虽然大多数从大唾液腺发展的病例是良性的,但所有轻微的sgt都是恶性的。与年轻人相比,老年患者更容易患上恶性肿瘤。本研究提供了唾液腺肿瘤的患病率、年龄相关发病率、性别分布和地理变异的见解。这有助于制定筛查、诊断和确定最佳治疗方案的指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological Profile of Salivary Gland Tumors in Southern Iranian Population: A Retrospective Study of 405 Cases.

Aims: Salivary gland tumors (SGTs) are a rare and diverse group of tumors that account for 3 to 10% of all head and neck malignancies. We aimed to conduct a comprehensive epidemiological analysis of SGTs in the south of Iran and compare the findings with previous reports from Iran and other parts of the world.

Methods: Using a retrospective study, 405 patients diagnosed with SGTs were observed over an eight-year period between April 2013 and October 2021 in Shiraz, Iran. Patients' demographic and clinicopathological features were obtained from patients' records. Quantitative and descriptive data analysis was performed using SPSS software.

Results: There were 302 benign (74.5%) and 103 (25.4%) malignant SGTs. Pleomorphic adenoma and Warthin's tumors were the most common benign SGTs (70.5% and 21.5%, respectively). The most common malignant SGTs were mucoepidermoid carcinoma and adenoid cystic carcinoma (26.2% and 22.3%, respectively). There was a statistically significant association between tumor origin and its malignancy status (p < 0.001). In addition, the results indicated that benign tumors were most commonly detected in the parotid gland (p < 0.05). The benign tumors were more frequently observed among the younger population (p = 0.006).

Conclusion: In summary, the findings of the current study were mainly consistent with the previous reports from Iran and the rest of the world. Benign tumors were the most prevalent type of SGTs, and the parotid gland was the most common site. While the majority of cases that developed from the major salivary glands were benign, all the minor SGTs were malignant. Older patients were more likely to develop malignant tumors compared to younger ones. This study provides insights into the prevalence, age-related incidence, gender distribution, and geographic variation of salivary gland tumors. This can be instrumental to develop a guideline for screening, diagnosis, and determining an optimal treatment.

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来源期刊
CiteScore
4.00
自引率
0.00%
发文量
10
审稿时长
20 weeks
期刊介绍: Journal of Cancer Epidemiology is a peer-reviewed, open access journal that publishes original research articles, review articles, case reports, and clinical studies in all areas of cancer epidemiology.
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