肌祖细胞融合在骨骼肌维持中的作用。

Q4 Biochemistry, Genetics and Molecular Biology

Results and Problems in Cell Differentiation Pub Date : 2024-01-01 DOI:10.1007/978-3-031-37936-9_13

Jarred M Whitlock

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引用次数: 0

摘要

骨骼肌拥有一个常驻的、多能的干细胞群，对其整个生命的修复和维持至关重要。在这里，我强调了这种干细胞群在肌肉修复和再生中的作用，并回顾了这一过程的遗传控制;这些细胞的活化、迁移、识别、粘附和融合的机制步骤;并讨论协调肌原细胞-细胞融合的膜信号的新识别，以及促进它的两部分融合原系统的识别。

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Muscle Progenitor Cell Fusion in the Maintenance of Skeletal Muscle.

Skeletal muscle possesses a resident, multipotent stem cell population that is essential for its repair and maintenance throughout life. Here I highlight the role of this stem cell population in muscle repair and regeneration and review the genetic control of the process; the mechanistic steps of activation, migration, recognition, adhesion, and fusion of these cells; and discuss the novel recognition of the membrane signaling that coordinates myogenic cell-cell fusion, as well as the identification of a two-part fusogen system that facilitates it.

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来源期刊

Results and Problems in Cell Differentiation Biochemistry, Genetics and Molecular Biology-Developmental Biology

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Results and Problems in Cell Differentiation is an up-to-date book series that presents and explores selected questions of cell and developmental biology. Each volume focuses on a single, well-defined topic. Reviews address basic questions and phenomena, but also provide concise information on the most recent advances. Together, the volumes provide a valuable overview of this exciting and dynamically expanding field.