[严重血小板减少伴缺铁性贫血1例及文献复习]。

Nassim Boutouchent, Maïssa Souissi, Gérard Buchonnet, Muriel Quillard, Victor Bobée
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引用次数: 0

摘要

缺铁是全世界贫血的主要原因,影响着大约6亿人。一旦建立,它通常表现为低色性小细胞性贫血,其严重程度取决于缺乏程度。这种贫血通常与血小板增多症有关,但与血小板减少症相关的存在是非常罕见的。在这里,我们报告了一个严重缺铁的病例,不典型的表现为双氧体减少症,包括严重贫血和深度血小板减少症,在补充铁后迅速解决。然后,我们讨论了存在的假设,以解释铁缺乏和血小板生成调节之间的联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Severe thrombopenia with iron deficiency anemia: about a case and literature review].

Iron deficiency is the leading cause of anemia worldwide, affecting approximately 600 million individuals. Once established, it typically manifests as a hypochromic microcytic anemia, the severity of which varies depending on the degree of deficiency. This anemia is frequently associated with thrombocytosis, but the presence of associated thrombocytopenia is much rarer. Here, we report a case of severe iron deficiency with an atypical presentation of bicytopenia, involving both severe anemia and profound thrombocytopenia, which rapidly resolved following iron supplementation. We then discuss the hypotheses that exist to explain the link between iron deficiency and regulation of thrombopoiesis.

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