早或晚服用长效抗精神病药物对精神分裂症患者照顾者负担的影响。

IF 2.1 3区 医学 Q3 PHARMACOLOGY & PHARMACY
Dilara Çırakman, Ersin Hatice Karslıoğlu, Neşe Burcu Bal, Ali Çayköylü
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引用次数: 0

摘要

精神分裂症早期的有效治疗对改善预后至关重要。精神分裂症也会影响患者的亲属。早期或晚期注射长效抗精神病药物(LAI-APs)对患者的影响已被证实,但对护理人员的影响尚不清楚。我们的目的是通过比较在诊断前5年开始使用ai - ap的患者和在诊断后5年开始使用ai - ap的患者,来确定开始使用ai - ap的时间如何影响照顾者的负担。根据开始LAI-AP的时间将患者分为“早期lai”和“晚期lai”。他们的照顾者也被分类为“早照顾者”和“晚照顾者”,并在照顾者负担方面进行比较。照顾者迟到组的生活质量、抑郁、焦虑和照顾者负担得分明显更差。开始使用ai - ap的时间和患者的功能水平是护理者负担的决定因素。据我们所知,这是第一个调查ai - ap启动时间对照顾者影响的研究。在早期阶段使用ai - ap与护理人员的更好结果相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of early or late initiation of long-acting antipsychotics on the caregiver burden in schizophrenia.

The effective treatment in the early stages of schizophrenia is of critical importance to improve the prognosis. Schizophrenia affects patients' relatives too. The effects of early or late initiation of long-acting injectable antipsychotics (LAI-APs) on the patient have been shown, yet their effects on the caregiver are still unknown. We aimed to determine how the time of initiation of LAI-APs affects the caregiver burden by comparing the patients who were started on LAI-APs in the first 5 years of diagnosis and those who were started at a later period. Patients were classified as 'early-LAI' and 'late-LAI' according to the time of initiation of a LAI-AP. Their caregivers were also classified as the same way, as 'caregiver-early' and 'caregiver-late' and were compared in terms of caregiver burden. The quality of life, depression, anxiety, and caregiver burden scores of the caregiver-late group were significantly worse. The time of initiation of LAI-APs and the functioning levels of the patients were found to be determinant factors for the caregiver burden. This is the first study to investigate the effects of LAI-AP's initiation time on the caregivers to our knowledge. The use of LAI-APs in the early stages is associated with better outcomes for the caregiver.

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来源期刊
CiteScore
4.40
自引率
23.10%
发文量
97
审稿时长
>12 weeks
期刊介绍: International Clinical Psychopharmacology provides an essential link between research and clinical practice throughout psychopharmacology. It reports on studies in human subjects, both healthy volunteers and patients, which relate the effects of drugs on psychological processes. A major objective of the journal is to publish fully refereed papers which throw light on the ways in which the study of psychotropic drugs can increase our understanding of psychopharmacology. To this end the journal publishes results of early Phase I and II studies, as well as those of controlled clinical trials of psychotropic drugs in Phase II and IV. Other topics covered include the epidemiology of psychotropic drug prescribing and drug taking, the sociology of psychotropic drugs including compliance, and research into the safety and adverse effects of these compounds.
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