R A Incalzi, C L Maini, L Fuso, A Giordano, P U Carbonin, G Galli
{"title":"衰老对纤毛粘液清除的影响。","authors":"R A Incalzi, C L Maini, L Fuso, A Giordano, P U Carbonin, G Galli","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.</p>","PeriodicalId":77698,"journal":{"name":"Comprehensive gerontology. Section A, Clinical and laboratory sciences","volume":"3 Suppl ","pages":"65-8"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of aging on mucociliary clearance.\",\"authors\":\"R A Incalzi, C L Maini, L Fuso, A Giordano, P U Carbonin, G Galli\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.</p>\",\"PeriodicalId\":77698,\"journal\":{\"name\":\"Comprehensive gerontology. Section A, Clinical and laboratory sciences\",\"volume\":\"3 Suppl \",\"pages\":\"65-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comprehensive gerontology. Section A, Clinical and laboratory sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comprehensive gerontology. Section A, Clinical and laboratory sciences","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.
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