犬肾排泄和计算机断层扫描对碘曲兰和iopamidol的增强作用。

Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband Pub Date : 1989-01-01

G Benness, C Evill, J Wilcox, R Hassam, E Arozoo

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引用次数: 0

摘要

比较非离子型、单聚体和二聚体造影剂(iopamidol和iotrolan)的肾脏排泄和计算机断层扫描(CT)增强，以确定后者是否对狗提供额外和持久的增强。排泄研究显示CM在血药浓度和肾排泄方面的表现几乎相同。然而，较低的碘曲兰渗透压使得肾髓质、乳头和尿液中的碘曲兰浓度较高。在CT或尿路造影中进一步增强肾脏的可能性很小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Renal excretion and computed tomography enhancement of iotrolan and iopamidol in dogs.

A comparison of the renal excretion and computed tomography (CT) enhancement of nonionic, monomer and dimer contrast media (CM) (iopamidol and iotrolan) was planned to determine if the latter provides additional and prolonged enhancement in dogs. The excretion studies show almost identical performance of both CM with respect to plasma concentration and renal excretion. However, the lower osmolality of iotrolan permits greater renal concentration in the medulla, papilla, and urine. The potential for this further enhancement of the kidney in CT or urography is marginal.

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Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband

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