念珠菌对酮康唑和伊曲康唑的体外敏感性比较。

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1989-09-01

Z Gwieździński, E Nierebińska, S Urbanowski

{"title":"念珠菌对酮康唑和伊曲康唑的体外敏感性比较。","authors":"Z Gwieździński, E Nierebińska, S Urbanowski","doi":"","DOIUrl":null,"url":null,"abstract":"The activity of ketoconazole and itraconazole against 102 strains of Candida sp. was compared in the investigation \"in vitro\". The investigational material was taken from patients with different types of mycosis. The values of MICs of ketoconazole and itraconazole were 0.04-100.0 micrograms/ml and 0.02-35.0 micrograms/ml, respectively. From the data obtained it is evident that the average efficacy of itraconazole is 3 to 10 times higher in comparison with ketoconazole though 8 strains (7, 8 percent) of investigated strains have shown greater sensitivity to ketoconazole.","PeriodicalId":20732,"journal":{"name":"Przeglad dermatologiczny","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Comparison of the susceptibility of Candida strains to ketoconazole and itraconazole in in vitro experiments].\",\"authors\":\"Z Gwieździński, E Nierebińska, S Urbanowski\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The activity of ketoconazole and itraconazole against 102 strains of Candida sp. was compared in the investigation \\\"in vitro\\\". The investigational material was taken from patients with different types of mycosis. The values of MICs of ketoconazole and itraconazole were 0.04-100.0 micrograms/ml and 0.02-35.0 micrograms/ml, respectively. From the data obtained it is evident that the average efficacy of itraconazole is 3 to 10 times higher in comparison with ketoconazole though 8 strains (7, 8 percent) of investigated strains have shown greater sensitivity to ketoconazole.\",\"PeriodicalId\":20732,\"journal\":{\"name\":\"Przeglad dermatologiczny\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.5000,\"publicationDate\":\"1989-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad dermatologiczny\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad dermatologiczny","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

比较了酮康唑和伊曲康唑对102株念珠菌的体外抑菌活性。研究材料取自不同类型的真菌病患者。酮康唑和伊曲康唑的mic值分别为0.04 ~ 100.0微克/ml和0.02 ~ 35.0微克/ml。从获得的数据可以明显看出，伊曲康唑的平均疗效比酮康唑高3至10倍，尽管8株(7.8%)被调查的菌株对酮康唑表现出更高的敏感性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Comparison of the susceptibility of Candida strains to ketoconazole and itraconazole in in vitro experiments].

The activity of ketoconazole and itraconazole against 102 strains of Candida sp. was compared in the investigation "in vitro". The investigational material was taken from patients with different types of mycosis. The values of MICs of ketoconazole and itraconazole were 0.04-100.0 micrograms/ml and 0.02-35.0 micrograms/ml, respectively. From the data obtained it is evident that the average efficacy of itraconazole is 3 to 10 times higher in comparison with ketoconazole though 8 strains (7, 8 percent) of investigated strains have shown greater sensitivity to ketoconazole.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.