A unique genetically engineered vaccine against human chorionic gonadotropin that prevents pregnancy without impairment of ovulation, hormonal profiles, and menstrual regularity

A brief overview is given of a vaccine that is competent to prevent pregnancy without any disturbance of normal ovulation, normal making of sex steroids, and menstrual regularity. It requires periodic intake and offers full privacy of use to the women. In order to render it reproducible on large scale, it has been made as a recombinant vaccine. To our knowledge, this is the first and only potential Birth Control vaccine at present in the world. This vaccine received the precious support from the International Committee on Contraception Research of the Population Council New York with clinical trials conducted in Finland, Sweden, Chile, and Brazil under eminent clinicians showing its safety and reversibility. Phase II trials in 3 major Institutions showed that it prevents unwanted pregnancy in sexually active women at antibody titers of 50 ng/ml and above. Fertility is regained with decline of antibody titers, and progeny born to previously immunized women is normal developmental land marks and cognitive ability with respect to their siblings.