J C Turakulov, K R Rakhimov, S F Karimova, L S Kuchkarova
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引用次数: 0
摘要
在哺乳期第1 ~ 21天每天给予50微克/100 g b.w.甲状腺素s.c.，可使α -葡萄糖苷酶(胰腺α -淀粉酶、肠道糖化酶)的诱导提前，β -半乳糖糖苷酶(肠道乳糖酶)的抑制提前。相比之下，甲状腺切除母鼠喂养的哺乳动物胰腺α -淀粉水解活性和肠道糖酶的诱导延迟，但乳糖酶的抑制改善。另一组甲状腺切除术母亲给予5微克/100克体重甲状腺素治疗，可防止甲状腺切除术母亲在哺乳期的这种影响。
Postnatal development of pancreatic alpha-amylase and intestinal saccharase and lactase in rat sucklings as related to thyroid function of mothers.
The treatment of lactating mothers with 50 micrograms/100 g b.w. thyroxine s.c. daily from the 1st to 21st day of lactation resulted in earlier induction of alpha-glucosidases (pancreatic alpha-amylase, intestinal saccharase) and in earlier repression of beta-galactosidases (intestinal lactase). In contrast, the sucklings fed by thyroidectomized mothers showed a delayed induction of pancreatic alpha-amylolytic activity and intestinal saccharase, but ameliorated the repression of lactase. The treatment of another group of thyroidectomized mothers with 5 micrograms/100 g b.w. thyroxine prevented such effects mothers of thyroidectomy in sucklings.
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