Psychoneuroendocrine stress-induced syndromes.

Psychoneuroendocrine stress-induced syndromes were characterised as expression of the activity of neuroendocrine transducers. A physiopathologic classification delineated the diseases which appeared as a result of the increase of the endocrine response to acute stress, i.e., catecholamine cardiomyopathy, reactive hypercortisolism, amenorrhea, infertility, sexual dysfunction of euthyroid sick syndrome in man and immunosuppression. The clinical diseases secondary to chronic stress, together with their physiopathologic therapy, i.e., central hypocorticism and psychosocial dwarfism, are described. They are produced by active inhibition of the endocrine response mechanism called by us: dysprotection.