拉合尔社会保障教学医院儿童年龄组登革热感染的临床分析

Shumaila Shahzeen, Khalid Mehmood Awan, None Amna Khalid, None Mohsin Ali, MEHWISH EJAZ, KHANDA FISHAN MUMTAZ
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摘要

登革热病毒感染是一种重要的热带疾病,已成为一个主要的全球公共卫生问题。本研究概述了登革热不断发展的临床谱,特别强调了不寻常的表现。方法:在儿科医学系、社会保障教学医院和拉合尔收集、汇编和分析了2022年季风和季风后季节120例登革热疑似病例的数据。血清学确诊为登革热感染的患者根据《登革热GCP指南2020》进行分类。研究临床参数。结果:在纳入研究的120例登革热疑似患者中,48例(40%)血清学证实登革热感染。120例患者中男性68例(56.66%),女性52例(43.33%)。66.66%为典型登革热,33.33%为登革出血热。DHF I/II级占25%,III级占8.33%。发热后最常见的症状为呕吐(85.4%)、腹痛(68.75%)、头痛(37.5%)、皮疹(20.83%)和瘙痒(16.66%)。43.75%的患者出现出血性表现。非典型表现4例(8.33%)。本研究的总体结果良好,无死亡率。 结论:登革热感染给卫生保健系统造成了巨大负担。它的范围从轻微的自限性疾病到严重的致命性疾病。它可能有多种多样的、多系统的表现,而这些表现可能被忽视。儿科医生对非典型表现应高度怀疑,因此准确的临床表现对患者的有效管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CLINICAL PROFILE OF DENGUE INFECTION IN PEDIATRIC AGE GROUP AT SOCIAL SECURITY TEACHING HOSPITAL,LAHORE
Dengue viral infection is a significant tropical disease and have become a major global public health concern. The present study sketches the evolving clinical spectrum of dengue especially highlighting the unusual manifestations. Methodology: Data of 120 suspected dengue fever cases was collected, compiled, and analysed during the monsoon and post-monsoon seasons in the year 2022 at the Department of Pediatric Medicine, Social Security Teaching Hospital, and Lahore. Patients with serological confirmation of dengue infection were classified according to Dengue GCP Guidelines 2020. Clinical parameters were studied. Results: Out of 120 suspected patients with dengue fever enrolled in the study, 48 (40%) had serologically confirmed dengue infection. Out of 120 cases, 68 (56.66%) patients were males and 52(43.33%) were females. 66.66 % patients had classical dengue fever while 33.33% had dengue hemorrhagic fever. DHF grade I/II was seen in 25 % cases and grade III DHF in 8.33% The most common symptoms after fever were vomiting (85.4% ), abdominal pain ( 68.75%), headache (37.5%), rash (20.83%) and itch (16.66%). Hemorrhagic manifestations were observed in 43.75% patients. Atypical manifestations were documented in 4 patients (8.33%) patients. Overall outcome in this study was good with no mortality. Conclusion: Dengue infection has posed a huge burden to the health-care system. Its spectrum ranges from mild self-limiting disease to severe fatal disease. It can have varied and multi-systemic manifestations which can go unnoticed. Pediatricians should have a high index of suspicion for atypical manifestations so revelation of the exact clinical profile is important for patient effective management.
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