-谷甾醇:一种有前途的营养保健品的结构、分析和药理潜力的机理研究

IF 0.8 Q4 NUTRITION & DIETETICS
Jyotsana Dwivedi, Pranjal Sachan, Pranay Wal, Bhagawati Saxena, Jayendra Kumar
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引用次数: 0

摘要

摘要:植物甾醇是一种天然存在于植物细胞膜中的生物活性物质,其原子组成类似于脊椎动物细胞产生的胆固醇。它们广泛存在于植物的膳食脂质中,如坚果、种子和橄榄油中的豆类。β-谷甾醇具有多种药理作用,对呼吸道和非酒精性脂肪肝疾病具有镇痛、免疫调节、抗菌、抗肿瘤、抗炎、降胆固醇、保肝和保护作用,并具有抗氧化和抗糖尿病活性。对人类的临床研究表明,它对前列腺癌有效,并具有抗炎和抗癌的特性。β-谷甾醇的药理学测试表明,其具有抗菌、抗炎、抗伤、抗癌、抗生育、血管生成、抗氧化、免疫调节、抗糖尿病和抗癌等一系列作用,且无明显毒性。许多作者已经创建了几种配方,但很少有关于该分子的分析,药理学和植物化学方法的学术评论。本文综述了β-谷甾醇的生物合成、药理学、营养应用、毒性、配方和分析技术等方面的研究进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A MechanisticApproach on Structural, Analytical and Pharmacological Potential of Beta-sitosterol: A Promising Nutraceutical
Abstract: Phytosterols are bioactive substances that are found spontaneously in the cell membranes of plants and have an atomic composition similar to cholesterol produced by vertebrate cells. They are widely distributed in dietary lipids from plants such as nuts, seeds, and beans with olive oil. β-sitosterol has a variation of pharmacological belongings, with analgesic, immunomodulatory, antiseptic, antineoplastic, anti-inflammatory, cholesterol decreasing, hepatoprotective, and protecting action concerning respiratory and non-alcoholic fatty liver disease illnesses, antioxidant, and anti-diabetic activity. Clinical studies on humans have shown that it works against prostate cancer and has anti-inflammatory and anti-cancer properties. Pharmacological testing of β-sitosterol demonstrated a range of actions including antibacterial, anti-inflammatory, antinociceptive, anticancer, antifertility, angiogenic, antioxidant, immunomodulatory, diabetes-fighting, and anticancer without significant toxicity. Several formulations have been created by numerous authors, but there are few scholarly reviews of the analytical, pharmacology, and phytochemistry methodologies for this molecule. In this review the literature on β- sitosterol, its biosynthesis, pharmacology, nutraceutical applications, toxicity, formulations, and analytical techniques are all highlighted.
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来源期刊
Current Nutrition & Food Science
Current Nutrition & Food Science NUTRITION & DIETETICS-
CiteScore
2.00
自引率
0.00%
发文量
144
期刊介绍: Current Nutrition & Food Science publishes frontier reviews on all the latest advances on basic and clinical nutrition and food sciences. The journal aims to publish the highest quality review articles dedicated to research in the field. The journal is essential reading for all nutrition and food scientists.
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