苦瓜籽油和苦瓜粉在身体磨砂膏配方中的优化

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES
Lina Winarti, Shifwatu Dzakkiyah, Eka Deddy Irawan, Erlia Narulita
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引用次数: 0

摘要

背景:苦瓜籽油和粉末是身体磨砂膏的潜在成分。种子含有脂肪酸,滋润皮肤,矿物质含量,去除死皮细胞,滋养皮肤。目的:确定苦瓜籽油粉在身体磨砂膏生产中的最佳效果。方法:身体磨砂膏采用W/O(油包水)膏底。采用单纯形点阵设计确定了五个公式。采用Draize皮肤试验法对大鼠(n = 3只,每个配方)进行刺激试验,计算初级皮肤刺激指数(Primary Dermal stimulation Index, PDII)。已获得女性参与者的知情同意进行享乐测试。结果:身体磨砂膏产生适当的感官,无刺激性,经离心和循环试验稳定。最佳配方为油5克,粉1克,pH值为5.21;粘度为205.33 dPa.s;铺展6.12cm;粘附时间19.86秒;洗涤速度20.60秒;颜色值为4.04;气味值2.90;纹理值为2.98。结论:优选的身体磨砂膏配方较好,可开发为身体磨砂制剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimisation of seed oil and powder of Momordica charantia in the formulation of body scrub cream
Background: Momordica charantia seed oil and powder are potential ingredients for a body scrub. The seeds contain fatty acids to moisturise the skin, and the mineral content to remove dead skin cells and nourish the skin.    Objective: To determine the optimal efficiency of Momordica charantia seed oil and powder on body scrub cream produce.    Methods: The body scrub used W/O (water-in-Oil) cream base. Simplex Lattice Design was used to determine five formulas. The irritation test with the Draize Skin Test method was carried out on rats (n = three, in each formula), and the Primary Dermal Irritation Index (PDII) was calculated. Informed consent from the female participants has been obtained for the hedonic test.     Results: The body scrub cream produced appropriate organoleptic, was not irritating, and was stable after centrifugation and cycling test. The optimum formula contained five grams of oil and one gram of powder with a pH of 5.21; viscosity of 205.33 dPa.s; spreading of 6.12cm; adhesion time of 19.86 seconds; rate of washing of 20.60 seconds; a colour value of 4.04; scent value of 2.90; and texture value of 2.98.    Conclusion: The optimised body scrub cream yielded a good formula which can be developed as a body scrub preparation.
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来源期刊
Pharmacy Education
Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-
CiteScore
0.80
自引率
20.00%
发文量
174
期刊介绍: Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.
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