黄菖蒲和木菖蒲提取物的植物化学成分及驱虫活性评价

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES

Pharmacy Education Pub Date : 2023-10-10 DOI:10.46542/pe.2023.234.284288

None Ghita Yogisuari, None Rocky Fahriar Reza, None Lailia Nur Rachma, None Tri Yudani Mardining Raras, None Antonius Nugraha Widhi Pratama, None Ari Satia Nugraha, None Bawon Triatmoko

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引用次数: 0

摘要

背景:有限的光谱和不适当的使用驱虫药导致驱虫药耐药。在印度尼西亚的药用植物中，Adiantum raddianum (Suplir)和Kibatalia arborea (Jelutong Pipit)显示出抗虫作用。目的:通过初步筛选，揭示白杨和白杨叶片的驱虫活性。方法:采用500µg/mL甲醇提取物微量稀释抗虫试验。秀丽隐杆线虫的死亡率表明有驱虫活性。采用薄层色谱法进行植物化学筛选。结果:两种提取物的甲醇提取物均具有驱虫活性，死亡率分别为14.941%和15.134%。这两种提取物都含有多酚、黄酮类化合物、萜类化合物和生物碱，这些物质只有在木参中才能找到。结论:本研究揭示了金针叶甲醇提取物具有驱虫活性，这可能与其植物化学成分的发现有关。

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Assessment of the phytochemicals and anthelminthic activities of Adiantum raddianum and Kibatalia arborea extracts

Background: A limited spectrum and inappropriate use of anthelmintics lead to anthelmintic resistance. Among Indonesian medicinal plants, Adiantum raddianum (Suplir) and Kibatalia arborea (Jelutong Pipit) have shown antihelmintic properties. Objective: To reveal the anthelmintic activity as preliminary screening of A. raddianum and K. arborea leaves. Method: This study used the antihelmintic microdilution test towards methanol extracts at 500 µg/mL. The mortality of Caenorhabditis elegans expresses the presence of anthelmintic activity. Phytochemical screening was determined using thin-layer chromatography. Result: The methanol extracts of both extracts had anthelmintic activity with mortality values of 14.941% and 15.134%, respectively. Both extracts contain polyphenols, flavonoids, terpenoids, and alkaloids found only in K. arborea. Conclusion: This study reveals that the methanol extract of A. raddianum and K. arborea leaves have anthelmintic activity, which could be related to the findings of phytochemical constituents.

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来源期刊

Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

0.80

自引率

20.00%

发文量

174

期刊介绍： Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.