{"title":"识别与胃肠道癌症相关的潜在危险因素:土耳其的一项病例对照研究","authors":"Sonay Goktas, Elif Gezginci","doi":"10.23950/jcmk/13691","DOIUrl":null,"url":null,"abstract":"<b>Objective: </b>Gastrointestinal cancers have different risk factors. However, it was clearly thought that the risk factors of these cancers should be determined by a case-control studies. The study aims to determine the potential risk factors associated with gastrointestinal cancers with a case-control study design.<br /> <b>Material and methods:</b> This case-control study was conducted with a total of 620 people applied to Department of General Surgery of two hospital in Turkey. The case group consisted of 310 patients diagnosed with gastrointestinal tract cancers. The control group consisted of 310 subjects without any history of cancer including gastrointestinal cancers. The data were collected with the Patient Identification Form including socio-demographic characteristics, and risk factors for gastrointestinal tract cancers.<br /> <b>Results:</b> The mean age of the case and control groups were 58.9±12.9 and 50.0±10.0, respectively. Although there was statistically significant differences in several factors compared, multivariate analysis identified male gender (OR=1.729, p=0.02), higher age (OR=1.068, p&lt;0.001), low body mass index (OR=1.110, p&lt;0.001), high number of children (OR=1.563, p&lt;0.001), cancer history in the family (OR=4.444, p&lt;0.001) and the presence of other chronic diseases (OR=6.314, p&lt;0.001) as risk factors. Mostly vegetable consumption (OR=2.923, p&lt;0.001) was also found to be a lower risk factor for gastrointestinal cancers.<br /> <b>Conclusion:</b> According to this study; age, gender, body mass index, number of children, family history of cancer, chronic diseases were among risk factors for gastrointestinal tract cancers. Vegetable consumption was an important factor to decrease gastrointestinal cancers.","PeriodicalId":32426,"journal":{"name":"Kazakstannyn Klinikalyk Medicinasy","volume":"31 3","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Identifying potential risk factors associated with gastrointestinal tract cancers: &nbsp;A case-control study in Turkey\",\"authors\":\"Sonay Goktas, Elif Gezginci\",\"doi\":\"10.23950/jcmk/13691\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<b>Objective: </b>Gastrointestinal cancers have different risk factors. However, it was clearly thought that the risk factors of these cancers should be determined by a case-control studies. The study aims to determine the potential risk factors associated with gastrointestinal cancers with a case-control study design.<br /> <b>Material and methods:</b> This case-control study was conducted with a total of 620 people applied to Department of General Surgery of two hospital in Turkey. The case group consisted of 310 patients diagnosed with gastrointestinal tract cancers. The control group consisted of 310 subjects without any history of cancer including gastrointestinal cancers. The data were collected with the Patient Identification Form including socio-demographic characteristics, and risk factors for gastrointestinal tract cancers.<br /> <b>Results:</b> The mean age of the case and control groups were 58.9±12.9 and 50.0±10.0, respectively. Although there was statistically significant differences in several factors compared, multivariate analysis identified male gender (OR=1.729, p=0.02), higher age (OR=1.068, p&lt;0.001), low body mass index (OR=1.110, p&lt;0.001), high number of children (OR=1.563, p&lt;0.001), cancer history in the family (OR=4.444, p&lt;0.001) and the presence of other chronic diseases (OR=6.314, p&lt;0.001) as risk factors. Mostly vegetable consumption (OR=2.923, p&lt;0.001) was also found to be a lower risk factor for gastrointestinal cancers.<br /> <b>Conclusion:</b> According to this study; age, gender, body mass index, number of children, family history of cancer, chronic diseases were among risk factors for gastrointestinal tract cancers. Vegetable consumption was an important factor to decrease gastrointestinal cancers.\",\"PeriodicalId\":32426,\"journal\":{\"name\":\"Kazakstannyn Klinikalyk Medicinasy\",\"volume\":\"31 3\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Kazakstannyn Klinikalyk Medicinasy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23950/jcmk/13691\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Kazakstannyn Klinikalyk Medicinasy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23950/jcmk/13691","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:胃肠道肿瘤具有不同的危险因素。然而,人们显然认为这些癌症的危险因素应该通过病例对照研究来确定。该研究旨在通过病例对照研究设计确定与胃肠道癌症相关的潜在危险因素。材料和方法:</b>本病例对照研究共纳入土耳其两家医院普外科620人。病例组包括310名被诊断为胃肠道癌症的患者。对照组包括310名没有任何癌症病史的受试者,包括胃肠道癌症。数据通过患者识别表收集,包括社会人口学特征和胃肠道癌症的危险因素。& lt; b>结果:& lt; / b>病例组和对照组平均年龄分别为58.9±12.9岁和50.0±10.0岁。虽然多个因素比较差异有统计学意义,但多因素分析发现男性(OR=1.729, p=0.02)、年龄较大(OR=1.068, p amp;lt;0.001)、体重指数较低(OR=1.110, p amp;lt;0.001)、子女较多(OR=1.563, p amp;lt;0.001)、家族癌症史(OR=4.444, p amp;lt;0.001)和存在其他慢性疾病(OR=6.314, p amp;lt;0.001)是危险因素。大多数蔬菜消费(OR=2.923, p<0.001)也被发现是胃肠道癌症的较低风险因素。& lt; b>结论:& lt; / b>根据这项研究;年龄、性别、体重指数、子女数量、癌症家族史、慢性疾病是胃肠道癌症的危险因素。食用蔬菜是减少胃肠道癌症的重要因素。
Identifying potential risk factors associated with gastrointestinal tract cancers: A case-control study in Turkey
Objective: Gastrointestinal cancers have different risk factors. However, it was clearly thought that the risk factors of these cancers should be determined by a case-control studies. The study aims to determine the potential risk factors associated with gastrointestinal cancers with a case-control study design. Material and methods: This case-control study was conducted with a total of 620 people applied to Department of General Surgery of two hospital in Turkey. The case group consisted of 310 patients diagnosed with gastrointestinal tract cancers. The control group consisted of 310 subjects without any history of cancer including gastrointestinal cancers. The data were collected with the Patient Identification Form including socio-demographic characteristics, and risk factors for gastrointestinal tract cancers. Results: The mean age of the case and control groups were 58.9±12.9 and 50.0±10.0, respectively. Although there was statistically significant differences in several factors compared, multivariate analysis identified male gender (OR=1.729, p=0.02), higher age (OR=1.068, p<0.001), low body mass index (OR=1.110, p<0.001), high number of children (OR=1.563, p<0.001), cancer history in the family (OR=4.444, p<0.001) and the presence of other chronic diseases (OR=6.314, p<0.001) as risk factors. Mostly vegetable consumption (OR=2.923, p<0.001) was also found to be a lower risk factor for gastrointestinal cancers. Conclusion: According to this study; age, gender, body mass index, number of children, family history of cancer, chronic diseases were among risk factors for gastrointestinal tract cancers. Vegetable consumption was an important factor to decrease gastrointestinal cancers.