尼日利亚两家三级医院患者接受的不同宫颈癌治疗与健康相关的生活质量

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

African Health Sciences Pub Date : 2023-10-11 DOI:10.4314/ahs.v23i3.32

Aliyu Samaila, Aminu A Biambo, Nuruddeen Usman, Usman M Aliyu, Adamu Abdullahi, Maxwell O Adibe

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引用次数: 0

摘要

背景:宫颈癌(CC)疾病及其治疗对幸存者有重要影响，特别是对生活质量(QoL)的影响。目的:评价尼日利亚两所三级医院CC患者与健康相关的生活质量(QoL)。方法:本研究采用前瞻性纵向设计。研究在索科托的乌斯马努·丹福迪约大学教学医院和尼日利亚西北部的扎里亚的艾哈迈德·贝罗大学教学医院进行。在基线和治疗后收集所有157例符合条件的cci患者的数据。数据分析使用SPSS V. 20 for windows进行适当的描述性和推断性统计。P<0.05认为有统计学意义。结果:78例(49.7%)患者以化疗(CT)为主。接受放化疗(CRT)和辅助化疗(CTS)的患者的平均总体健康相关生活质量比各自的基线评分提高了0.138(t=8.456, p<0.001)和0.138(t= 6.489, p<0.001)，增幅最大。接受CT治疗的患者与健康相关的平均总体生活质量较基线增加最少，为0.095 (t=4.574, p<0.001)。结论:放化疗和辅助化疗与平均总体健康相关生活质量的最高增加相关。化疗与平均总体健康相关生活质量的增加相关最小。关键词:宫颈癌;生活质量;疗法。

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Health-related quality of life associated with different cervical cancer therapies received by patients in two Nigerian tertiary hospitals

Background: There are important consequences from cervical cancer (CC) disease and its treatment among survivors, especiallythe impact on quality of life (QoL). Objective: To evaluate the health-related QoL associated with different CC therapies received by patients in two Nigerian tertiaryhospitals. Methods: This study employed a prospective longitudinal design. It was conducted at Usmanu Danfodiyo University TeachingHospital, Sokoto and Ahmadu Bello University Teaching Hospital Zaria, North-Western Nigeria. Data of all the 157 eligible CCpatients were collected at baseline and after therapy. Data analysis was done with appropriate descriptive and inferential statisticsusing SPSS V. 20 for windows. P<0.05 was considered statistically significant. Results: Chemotherapy (CT) was the major therapy option received by 78(49.7%) of the patients. Patients who received chemoradiation therapy (CRT) and adjuvant chemotherapy (CTS) had the highest increase in mean overall health-related QoL of 0.138(t=8.456, p<0.001) and 0.138 (t=6.489, p<0.001) higher than their respective baseline scores. Patients who received CT had theleast increase in mean overall health-related QoL of 0.095 (t=4.574, p<0.001) from baseline. Conclusion: Chemoradiation therapy and adjuvant chemotherapy were associated with highest increase in mean overallhealth-related QoL. Chemotherapy was associated with the least increase in mean overall health-related QoL. Keywords: Cervical cancer; quality of life; therapies.

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来源期刊

African Health Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

179

审稿时长

>12 weeks

期刊介绍： The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.