番荔枝提取物生物活性成分鉴定及对人乳腺癌细胞的体外细胞毒性分析

Q4 Agricultural and Biological Sciences
S. Selvakumar, A. Mounisha, J. Joshna Florence
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引用次数: 0

摘要

本研究旨在探讨番荔枝三氯甲烷提取物的生物活性成分及其体外细胞毒性。材料与方法:以药用植物番槐氯仿提取物的空中部位为调控物,采用vero法停止体外细胞毒性分析,分别采用气相色谱-质谱法和MTT法对人乳腺MCF-7细胞株进行分析。结果:本研究设想了12种植物化合物及其对Vero以及人乳腺癌和MCF-7细胞系的显著细胞毒作用。结论:草药植物作为原药的潜在药用价值已被广泛研究。显然,从草药来源的天然产物将继续是极其重要的医药制剂的来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Identification of Bioactive Components and in vitro Cytotoxicity Analysis of Annona squamosa Extract on Human Breast Cancer Cells
The present study is to explore to determine the bioactive components and in vitro cytotoxicity of the chloroform extract of Annona squamosa analyzed. Materials and Methods: The aerial parts of chloroform extract of the medicinal plant Annona squamosa were used to regulate the bioactive components and their in vitro analysis of cytotoxicity was ceased by vero and human breast MCF-7 cell lines were analyzed by gas chromatography and mass spectrometry and MTT assay respectively. Results: The present study envisages 12 phytocompounds and their significant cytotoxic role on Vero as well as human breast carcinoma and MCF-7 cell lines. Conclusion: Herbal medicinal plants have been extensively studied for their possible medicinal value as primary source drugs. Obviously, the natural products from the herbal medicinal sources will continue to be extremely important as sources of medicinal agents.
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来源期刊
Plant Cell Biotechnology and Molecular Biology
Plant Cell Biotechnology and Molecular Biology Agricultural and Biological Sciences-Horticulture
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