有症状和无症状感染者血清抗体的筛选

Q4 Medicine
Shaimaa, A. Shlash, Huda, A. Saleh, Fatima, R. Almashhady
{"title":"有症状和无症状感染者血清抗体的筛选","authors":"Shaimaa, A. Shlash, Huda, A. Saleh, Fatima, R. Almashhady","doi":"10.21931/rb/css/2023.08.03.14","DOIUrl":null,"url":null,"abstract":"Hymenolepis nana is a common parasitic disease that spreads mainly to children. The present study aims to circulate anti-parasite antibody responses against H.nana in the symptomatic and asymptomatic IN children with assured hymenolepiasis examined in Al-Najaf province. Symptomatic patients were explicitly used as follows: the existence of H.nana eggs in the feces with more symptoms such as diarrhea, abdominal pain, losing weight, flatulency, appetite loss, and nausea. Antiparasite of the humoral immune response had been measured using indirect immunofluorescence (IFA) and ELISA. A significant disparity was noticed in the antiparasite antibody response when measuring the IFA of the asymptomatic and symptomatic patients. Over 37% of asymptomatic patients had a titer of 1:500 or lower, and more than 28% of symptomatic patients had a titer of 1:8000 or higher. When measured by ELISA, the circulation of anti-parasite overall IgM and IgA is significantly higher in symptomatic than asymptomatic patients, as regarding upper egg production showed in the symptomatic people. Keywords: Hymenolepis nana, Cysticercoids, asymptomatic and symptomatic patients, Antibody response.","PeriodicalId":52287,"journal":{"name":"Revista Bionatura","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Screening of serum antibody to symptomatic and asymptomatic patients with Hymenolepis nana\",\"authors\":\"Shaimaa, A. Shlash, Huda, A. Saleh, Fatima, R. Almashhady\",\"doi\":\"10.21931/rb/css/2023.08.03.14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hymenolepis nana is a common parasitic disease that spreads mainly to children. The present study aims to circulate anti-parasite antibody responses against H.nana in the symptomatic and asymptomatic IN children with assured hymenolepiasis examined in Al-Najaf province. Symptomatic patients were explicitly used as follows: the existence of H.nana eggs in the feces with more symptoms such as diarrhea, abdominal pain, losing weight, flatulency, appetite loss, and nausea. Antiparasite of the humoral immune response had been measured using indirect immunofluorescence (IFA) and ELISA. A significant disparity was noticed in the antiparasite antibody response when measuring the IFA of the asymptomatic and symptomatic patients. Over 37% of asymptomatic patients had a titer of 1:500 or lower, and more than 28% of symptomatic patients had a titer of 1:8000 or higher. When measured by ELISA, the circulation of anti-parasite overall IgM and IgA is significantly higher in symptomatic than asymptomatic patients, as regarding upper egg production showed in the symptomatic people. Keywords: Hymenolepis nana, Cysticercoids, asymptomatic and symptomatic patients, Antibody response.\",\"PeriodicalId\":52287,\"journal\":{\"name\":\"Revista Bionatura\",\"volume\":\"13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Bionatura\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21931/rb/css/2023.08.03.14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Bionatura","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21931/rb/css/2023.08.03.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1

摘要

无性膜膜绦虫是一种常见的寄生虫病,主要传播给儿童。本研究的目的是在Al-Najaf省检查的有症状和无症状的确诊膜膜癣儿童中传播针对H.nana的抗寄生虫抗体反应。有症状的患者明确为:粪便中存在H.nana卵,以腹泻、腹痛、体重减轻、肠胃胀气、食欲不振、恶心等症状较多。采用间接免疫荧光法(IFA)和酶联免疫吸附法(ELISA)检测抗寄生虫体液免疫反应。在测量无症状和有症状患者的IFA时,发现抗寄生虫抗体反应有显著差异。超过37%的无症状患者的滴度为1:500或更低,超过28%的有症状患者的滴度为1:8000或更高。ELISA检测发现,有症状者抗寄生虫总IgM和IgA循环明显高于无症状者,有症状者产蛋量较高。关键词:微小膜膜绦虫,囊虫,无症状和有症状患者,抗体反应
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening of serum antibody to symptomatic and asymptomatic patients with Hymenolepis nana
Hymenolepis nana is a common parasitic disease that spreads mainly to children. The present study aims to circulate anti-parasite antibody responses against H.nana in the symptomatic and asymptomatic IN children with assured hymenolepiasis examined in Al-Najaf province. Symptomatic patients were explicitly used as follows: the existence of H.nana eggs in the feces with more symptoms such as diarrhea, abdominal pain, losing weight, flatulency, appetite loss, and nausea. Antiparasite of the humoral immune response had been measured using indirect immunofluorescence (IFA) and ELISA. A significant disparity was noticed in the antiparasite antibody response when measuring the IFA of the asymptomatic and symptomatic patients. Over 37% of asymptomatic patients had a titer of 1:500 or lower, and more than 28% of symptomatic patients had a titer of 1:8000 or higher. When measured by ELISA, the circulation of anti-parasite overall IgM and IgA is significantly higher in symptomatic than asymptomatic patients, as regarding upper egg production showed in the symptomatic people. Keywords: Hymenolepis nana, Cysticercoids, asymptomatic and symptomatic patients, Antibody response.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Revista Bionatura
Revista Bionatura Medicine-Epidemiology
CiteScore
0.50
自引率
0.00%
发文量
144
审稿时长
8 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信