A Critical Study on the Synthetic and Herbal Medication Pattern in the Management of Psoriasis

Abstract:: Psoriasis is a persistent skin illness that causes dense, shimmering flakes, irritable, dry, and red patches as a result of the fast buildup of skin cells. It is an autoimmune skin condition that is incurable, non-contagious, and relapsing-remitting. Typically, a remission phase lasts one to twelve months. Psoriasis is caused by a number of cellular mechanisms, and it has been hypothesised that T lymphocytes, keratinocytes, allergen cells, Langerhans cells, natural killer cells, phagocytes, a number of Th1-type chemokines, in addition to growth factors like endothelial proliferation factor and keratinocytes growth factor, among others, are key players in the development of psoriasis. Numerous synthetic medicinal drugs have been documented to have the side effects of psoriasis. Due to the safety and accessibility, herbal medications may hold promise as possible anti-psoriatic molecules. Before creating a potential herbal drug, it is important to thoroughly examine the key players in the evolution of psoriasis, such as T-cell stimulation, transportation, and cytokinase inhibition. The purpose of this review is to investigate how psoriasis spreads and becomes activated, as well as how certain medications might exacerbate the condition and how certain plant resources may be used to treat psoriasis. To create a potent, secure, and dependable treatment, more scientific research on these herbal resources is required.