金钟勋博士

None Jong Hoon Kim
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引用次数: 0

摘要

Jong Hoon Kim博士是韩国延世大学皮肤病学和皮肤生物学研究所的助理教授。2013年至2016年完成博士及博士后项目,主要研究方向为T细胞免疫学。他最初的研究旨在剖析牛皮癣中t细胞活化的机制。通过他的工作,他发现tcr介导的PD-1+IL-17A+ T细胞的激活有助于小鼠牛皮癣的疾病活性,独立于il -23介导的激活(J Allergy clinin Immunol. 2016)。本研究为人类银屑病皮肤中PD-1+常驻记忆Tc17细胞的产生机制提供了新的见解。他还通过收集肝移植过程中的肝灌注液对人类T细胞进行了研究,确定了健康和患病条件下肝脏驻留CD69+CD103-CD8+ T细胞的特异性特征(J Hepatol. 2020)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dr. Jong Hoon Kim
Dr. Jong Hoon Kim M.D. Ph.D. is an Assistant Professor in the Department of Dermatology and Cutaneous Biology Research Institute at Yonsei University in South Korea. He completed his Ph.D. and postdoctoral projects between 2013 and 2016, which focused on the study of T cell immunology. His initial research aimed to dissect the mechanism of T-cell activation in psoriasis. Through his work, he found that TCR-mediated activation of PD-1+IL-17A+ T cells contributes to disease activity in murine psoriasis, independent of IL-23-mediated activation (J Allergy Clin Immunol. 2016). This study provided insights into the mechanism of generating PD-1+ resident memory Tc17 cells observed in human psoriatic skin. He also conducted a study on human T cells by collecting liver perfusate during liver transplantation, where he identified specific features of liverresident CD69+CD103-CD8+ T cells under healthy and diseased conditions (J Hepatol. 2020).
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