肾脏和泌尿道的先天性异常:连续的护理

IF 2.8 3区医学 Q2 UROLOGY & NEPHROLOGY

Seminars in nephrology Pub Date : 2023-10-01 DOI:10.1016/j.semnephrol.2023.151433

Bärbel Lange-Sperandio, Hans-Joachim Anders, Maximilian Stehr, Robert L. Chevalier, Richard Klaus

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引用次数: 0

摘要

先天性肾和尿路异常(ckut)是儿童和青少年肾衰竭的主要原因。CAKUT描述了广泛的结构障碍与产前起源。CAKUT的病因是多因素的，包括影响肾脏发育以及上、下尿路发育的环境、非遗传和遗传原因。治疗ckut患者的成人肾病学家可能会受到他们不熟悉的潜在疾病和儿童期慢性肾病并发症积累的挑战。本文讨论了ckut的病因和表现，儿童期和青春期的病程，以及ckut患者的成人问题，包括CKD并发症，泌尿系统干预和遗传咨询。CAKUT患者从儿科到成人护理的顺利过渡可能具有挑战性。Semin Nephrol 43:x-xx©2023 Elsevier Inc.。版权所有。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Congenital Anomalies of the Kidney and Urinary Tract: A Continuum of Care

Congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of kidney failure in children and adolescents. CAKUT describes a wide spectrum of structural disorders with a prenatal origin. The etiology of CAKUT is multifactorial, including environmental, nongenetic, and genetic causes that impact kidney development as well as upper and lower urinary tract development. Adult nephrologists who treat patients with CAKUT may be challenged by the underlying diseases they are not familiar with and the accumulation of chronic kidney disease complications in childhood. This article discusses CAKUT etiology and presentation, the course during childhood and adolescence, as well as adult issues in CAKUT patients including CKD complications, urologic interventions, and genetic counseling. A smooth transition of CAKUT patients from pediatric to adult care can be challenging. Semin Nephrol 43:x-xx © 2023 Elsevier Inc. All rights reserved.

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来源期刊

Seminars in nephrology 医学-泌尿学与肾脏学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Seminars in Nephrology is a timely source for the publication of new concepts and research findings relevant to the clinical practice of nephrology. Each issue is an organized compendium of practical information that serves as a lasting reference for nephrologists, internists and physicians in training.