使用氢氧化钙膏改变根管的生物膜

A. A. Raskov, S. N. Gromova, V. A. Kreneva, S. B. Petrov, E. P. Kolevatykh, V. A. Razumny
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引用次数: 0

摘要

的目标。探讨含氢氧化钙糊剂对根管治疗过程中根管生物膜环境变化的影响。材料和方法。29例68根管诊断为慢性根尖牙周炎的患者纳入研究。根据诊断的临床建议(治疗方案)进行治疗:“根尖周围组织疾病”,由2014年9月30日“俄罗斯口腔医学会”公共协会理事会第18号决议批准,2018年8月2日更新。在根管内注射氢氧化钙糊剂前后取根管内容物生物材料14 d。采用以下方法:临床、微生物平板计数、革兰氏阳性和革兰氏阴性微生物、真菌测定,同时进行聚合酶链反应(PCR)。数据的统计分析包括描述会计特征,评估研究指标变化的统计显著性。选择差异统计显著性的临界水平(p),取p <0.05. 结果。根据所进行的研究,统计分析显示,所有研究的微生物指标呈统计学显著的负动态。结论。所获得的数据使我们得出结论,含有氢氧化钙的制剂可用于治疗诊断为慢性根尖牙周炎的患者作为管内药物,因为它在有限的区域内具有杀菌作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changing the biofilm of the root canals using a paste of calcium hydroxide
Aim. To evaluate the environmental change of root canal biofilm during primary endodontic treatment under the influence of paste containing calcium hydroxide. Materials and methods. Twenty-nine patients with 68 root canals diagnosed with Chronic Apical Periodontitis were included in the study. Treatment was carried out according to clinical recommendations (treatment regimen) for the diagnosis: "Diseases of periapical tissues", approved by Resolution No. 18 of the Council of the Association of Public Association "Stomatological Association of Russia" of September 30, 2014, updated on August 02, 2018. Biological material of the root canal contents was taken before and after injection of calcium hydroxide paste into the root canal for 14 days. The following methods were used: clinical, microbiological – plate count, gram-positive and gram-negative microorganisms, fungi were determined, and polymerase chain reaction (PCR) was performed at the same time. Statistical analysis of data included description of accounting features, assessment of statistical significance of changes in the studied indicators. The critical level of statistical significance of differences (p) was chosen with a value of p < 0.05. Results. According to the conducted studies, statistical analysis showed statistically significant negative dynamics for all studied microbiological indicators. Conclusions. The obtained data allow us to conclude that preparations containing calcium hydroxide can be used in the treatment of patients diagnosed with chronic apical periodontitis as an intracanalicular drug, because it has a bactericidal effect on a limited area.
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