一种简便、机械化学、无溶剂和无催化剂的功能化4-噻唑烷酮合成方法

IF 2 Q2 CHEMISTRY, ORGANIC

SynOpen Pub Date : 2023-10-12 DOI:10.1055/a-2190-9678

Simranpreet K Wahan, Pooja A Chawla, Parvesh Singh, Rupesh Kumar, Gaurav Bhargava

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引用次数: 0

摘要

探索了一种基于研钵机械化学法制备多种功能化4-噻唑烷酮的绿色环保方法。所开发的方法不需要使用有害或昂贵的试剂和有机溶剂，反应时间非常短，易于分离。探索更环保的方法来合成4-噻唑烷酮是一个重要的方面，他们有用的宝贵的药理学性质。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A FACILE, MECHANOCHEMICAL, SOLVENT AND CATALYST-FREE SYNTHESIS OF FUNCTIONALIZED 4-THIAZOLIDINONES

A highly eco-friendly greener approach based on the mechanochemical method using mortar and pestle is explored for the preparation of a variety of functionalized 4-thiazolidinones. The developed methodology does not require the use of harmful or expensive reagents and organic solvents and requires very less reaction time with easy isolation. The explored greener approach for the synthesis of 4-thiazolidinones is an important in terms of their usefulness for their valuable pharmacological properties.

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来源期刊

SynOpen CHEMISTRY, ORGANIC-

CiteScore

2.30

自引率

4.00%

发文量

审稿时长

6 weeks