一例与甲氨蝶呤相关的淋巴组织增生性疾病患者停药后病情得到缓解：有关 105 例日本病例临床特征的文献综述

IF 1.1 Q4 ALLERGY

Journal of Cutaneous Immunology and Allergy Pub Date : 2023-09-11 DOI:10.1002/cia2.12324

Shintaro Higashida MD, Erina Kodaka MD, Hiromichi Iwasaki MD, PhD, Hideaki Sakai MD, Noritaka Oyama MD, PhD, Minoru Hasegawa MD, PhD

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引用次数: 0

摘要

我们报告了一例类风湿性关节炎患者，该患者在接受甲氨蝶呤（MTX）单药治疗期间出现皮肤弥漫性大B细胞淋巴瘤，停药后病情迅速缓解。我们对 100 多例日本病例的文献进行了回顾，重新审视了治疗耐药性和/或淋巴瘤反复复发的潜在风险，尤其是对停用 MTX 无反应或接受较高累积剂量治疗的病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A case of methotrexate-related lymphoproliferative disorder resolved with discontinuation of the drug: A literature review for clinical characteristics in 105 Japanese cases

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A case of methotrexate-related lymphoproliferative disorder resolved with discontinuation of the drug: A literature review for clinical characteristics in 105 Japanese cases

We report a case of rheumatoid arthritis who developed cutaneous diffuse large B-cell lymphoma during methotrexate (MTX) monotherapy with prompt resolution after discontinuation of the drug. Our literature review of over 100 reported Japanese cases revisited the potential risk of treatment resistance and/or repeated recurrence of lymphomas, particularly in cases that were unresponsive to the withdrawal of MTX or received a higher cumulative dose.

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来源期刊

Journal of Cutaneous Immunology and Allergy Medicine-Dermatology

CiteScore

0.60

自引率

10.00%

发文量

审稿时长

12 weeks