{"title":"面对钩端螺旋体病:一种表现为血栓性微血管病变和多器官功能障碍的热带疾病","authors":"Arnab Choudhury, Ajinkya Rahatgaonkar","doi":"10.47363/jmhc/2023(5)244","DOIUrl":null,"url":null,"abstract":"This case report outlines the presentation and clinical course of a 28-year-old lady with previously unremarkable health, who developed symptoms including fever, headache, gastrointestinal distress, and jaundice. Her condition rapidly deteriorated, culminating to multisystem involvement in the form of severe anaemia, acute kidney injury, thrombocytopenia, and acute respiratory distress syndrome (ARDS). The aetiology was confirmed as leptospirosis. Despite optimum therapeutic measures, including mechanical ventilation and plasmapheresis in view of suspected thrombotic microangiopathy, the patient succumbed to the complications of severe ARDS. This case underscores the imperative of early identification and tailored management strategies for intricate multi-system involvement in conditions like leptospirosis.","PeriodicalId":93468,"journal":{"name":"Journal of medicine and healthcare","volume":"14 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Confronting Leptospirosis: A Tropical Illness Presenting with Thrombotic Microangiopathy and Multiorgan Dysfunction\",\"authors\":\"Arnab Choudhury, Ajinkya Rahatgaonkar\",\"doi\":\"10.47363/jmhc/2023(5)244\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This case report outlines the presentation and clinical course of a 28-year-old lady with previously unremarkable health, who developed symptoms including fever, headache, gastrointestinal distress, and jaundice. Her condition rapidly deteriorated, culminating to multisystem involvement in the form of severe anaemia, acute kidney injury, thrombocytopenia, and acute respiratory distress syndrome (ARDS). The aetiology was confirmed as leptospirosis. Despite optimum therapeutic measures, including mechanical ventilation and plasmapheresis in view of suspected thrombotic microangiopathy, the patient succumbed to the complications of severe ARDS. This case underscores the imperative of early identification and tailored management strategies for intricate multi-system involvement in conditions like leptospirosis.\",\"PeriodicalId\":93468,\"journal\":{\"name\":\"Journal of medicine and healthcare\",\"volume\":\"14 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of medicine and healthcare\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47363/jmhc/2023(5)244\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medicine and healthcare","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47363/jmhc/2023(5)244","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Confronting Leptospirosis: A Tropical Illness Presenting with Thrombotic Microangiopathy and Multiorgan Dysfunction
This case report outlines the presentation and clinical course of a 28-year-old lady with previously unremarkable health, who developed symptoms including fever, headache, gastrointestinal distress, and jaundice. Her condition rapidly deteriorated, culminating to multisystem involvement in the form of severe anaemia, acute kidney injury, thrombocytopenia, and acute respiratory distress syndrome (ARDS). The aetiology was confirmed as leptospirosis. Despite optimum therapeutic measures, including mechanical ventilation and plasmapheresis in view of suspected thrombotic microangiopathy, the patient succumbed to the complications of severe ARDS. This case underscores the imperative of early identification and tailored management strategies for intricate multi-system involvement in conditions like leptospirosis.