中性粒细胞与妊娠相关疟疾

Moussa Djimde, Kassoum Kayentao, Charles Arama, Alassane Dicko, Petra F. Mens, Henk H.D.F. Schallig
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摘要

目的:生活在恶性疟原虫传播地区的孕妇暴露于疟疾及其对妊娠结局的有害后果。中性粒细胞是血液中最丰富的白细胞(WBC),是对抗感染的先天免疫关键效应器。研究中性粒细胞在疟疾中的作用已经做了大量的工作,但对妊娠相关性疟疾(PAM)的研究却很少。这篇综述的重点是中性粒细胞在妊娠期间对疟疾的反应,这可能有助于我们了解它们的动态和对妊娠结局的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neutrophils and Pregnancy-Associated Malaria
Purpose: Pregnant women living in areas with transmission of Plasmodium falciparum are exposed to malaria and its harmful consequences on pregnancy outcomes. Neutrophils are the most abundant white blood cells (WBC) in the bloodstream and are innate immune key effectors against infections. Substantial work has been done to study the role of neutrophils in malaria, but little on pregnancy-associated malaria (PAM). This review focuses on neutrophil responses to malaria during pregnancy that may help us to understand their dynamics and effects on pregnancy outcomes.
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