辣木叶提取物对高血糖大鼠丙二醛(MDA)和谷胱甘肽过氧化物酶(GSH-Px)水平的抗氧化作用:系统文献综述

Q4 Health Professions
Asti Marian, Eti Yerizel, Hudila Rif
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引用次数: 0

摘要

高血糖是糖尿病(Diabetes Mellitus, DM)的临床指标,糖尿病患者慢性高血糖与器官系统损伤有关,如肾、眼、神经、血管受损,甚至通过氧化应激过程导致抗氧化剂与自由基失衡而死亡。辣木(Moringa Oleifera, MO)是一种含有抗氧化剂的植物,已被用作食品原料。这种植物具有低毒性、天然抗氧化剂和重要的生物活性植物化学物质,是替代合成药物的天然疗法的极佳来源。辣木叶片中的外源抗氧化剂可能具有清除自由基的潜力。通过检索Research Gate、Science Direct、PubMed和Google Scholar数据库,系统回顾了2017年至2023年间发表的研究。符合纳入标准的研究被纳入审查。文献综述结果表明,辣木叶提取物具有降低血糖、降低丙二醛(MDA)、增加体内抗氧化剂(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)的作用。关键词:高血糖,糖尿病,辣木叶提取物,氧化应激,抗氧化剂
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Moringa Oleifera Leaf Extract as an Antioxidant on Malondialdehyde (MDA) and Glutathione Peroxidase (GSH-Px) Levels in Rats with Hyperglycemia: A Systematic Literature Review
Hyperglycaemia is a clinical indicator of Diabetes Mellitus (DM), chronic hyperglycemia in diabetes is associated with damage to organ systems, such as kidney damage, eyes, nerves, and blood vessels, and even death through oxidative stress processes, resulting in an imbalance between antioxidants and free radicals. One of the plants that contain antioxidants is Moringa Oleifera (MO), MO has been utilized as a food source material. This plant has low toxicity, natural antioxidants, and important bioactive phytochemicals and is an excellent source of alternative natural therapies to synthetic drugs. Exogenous antioxidants in Moringa leaves may have potential as free radical scavengers. Studies published between 2017 and 2023 were systematically reviewed through identification in Research Gate, Science Direct, PubMed, and Google Scholar databases. Studies that met the inclusion criteria were included for review. The results of the literature review of the articles carried out can be concluded that the administration of moringa leaf extract is able to reduce blood sugar levels, reduce MDA levels and increase antioxidants in the body, such as Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GSH-Px). Keywords: Hyperglycaemia, Diabetes, Leaf Extract Moringa Oleifera, Oxidative Stress, Antioxidant
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来源期刊
International Journal of Current Research and Review
International Journal of Current Research and Review Health Professions-Health Professions (miscellaneous)
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