Synthesis Of Graphene Oxide Modified Polyaniline And Its Electrochemical Application For Detection of Nitric Oxide

Nitric oxide plays a crucial and important role in cellular physiology and also functions as a human cancer signaling molecule. Nitric oxide (NO) also exhibits antimicrobial and antitumor properties. However, conventional detection methods have their own limitations in the detection of NO at low concentrations because of its high reactivity and low lifetime. Here, we report a strategy to graphene oxide (GO)-modified polyaniline with efficiency to detect NO at a low concentration by electrocatalytic method. For this study we prepared graphene oxide polyaniline (GO-PANI) which has higher stability and stronger catalytic activity towards the oxidation of nitric oxide (NO).The synthesized compound was characterized by field emission scanning electron microscopy (FESEM) and UV-visible spectroscopy. With further modification of Nafion, the determination of NO in PBS with different concentration .This investigation offers a different method for determination of NO.