骨骼肌减少症对老年虚弱慢性肾病患者预后的影响

Lei Ran, Lei Wang, Tingting Cai
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摘要

目的:探讨老年体弱慢性肾病患者肌肉减少症对预后的影响。方法:2020年6月至2022年7月共纳入98例老年体弱慢性肾脏疾病患者。将患者随机分为研究组48例,对照组50例。对照组仅接受慢性肾病常规治疗。研究组在常规治疗慢性肾脏疾病的基础上,增加肌少症干预治疗。观察分析两组患者的生活质量评分、肌量、肌力、肾功能、并发症发生率。结果:研究组患者的生活质量评分、肌量、肌力、肾功能均显著优于对照组(P <0.05);研究组并发症发生率为12.5%,明显低于对照组的36% (P <0.05)。结论:骨骼肌减少症与老年虚弱慢性肾病患者有密切关系。老年慢性肾病患者骨骼肌减少症会进一步加重虚弱症状,增加并发症的发生风险。对于老年慢性肾病患者,应尽早筛查和干预肌肉减少症,以改善患者的预后和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of Sarcopenia on Prognosis in Frail Elderly Patients with Chronic Kidney Disease
Objective: To investigate the impact of sarcopenia on the prognosis of frail elderly patients with chronic kidney disease. Methods: A total of 98 elderly frail patients with chronic kidney disease were included in this study from June 2020 to July 2022. The patients were randomly divided into a study group of 48 cases and a control group of 50 cases. The control group only received conventional treatment for chronic kidney disease. On the basis of conventional treatment for chronic kidney disease, the study group added sarcopenia intervention treatment. The quality-of-life scores, muscle mass and muscle strength, renal function, and incidence of complications of the two groups were observed and analyzed. Results: The quality-of-life score, muscle mass and muscle strength, and renal function of the study group were significantly better than those of the control group (P < 0.05); the incidence of complications in the study group was 12.5%, which was significantly lower than that of the control group 36% of the group (P < 0.05). Conclusion: There is a close relationship between sarcopenia and frail elderly patients with chronic kidney disease. Sarcopenia will further aggravate the frailty symptoms and increase the risk of complications in elderly patients with chronic kidney disease. For elderly patients with chronic kidney disease, sarcopenia should be screened and intervened as early as possible to improve the prognosis and quality of life of the patients.
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