中国广东省已发现的早期天花病例的流行病学和特征:对预防和控制的影响

IF 3.5 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Yinan Zong , Yuwei Yang , Dongfeng Kong , Jianxiong Xu , Zimian Liang , Fengxiang Shi , Jianhua Huang , Min Kang , Haojie Zhong , Wenjia Liang , Yan Li
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引用次数: 0

摘要

2023 年 6 月,2022 年全球猴痘疫情开始影响广东省,这是中国大陆最早报告猴痘病例的地区之一。截至2023年7月10日,广东省共报告93例猴痘病例。本研究通过收集和分析人口统计学、性行为、病史、旅行史、临床症状、诊断途径和过程等方面的数据,描述了这些患者的流行病学特征。93 例艾滋病病毒感染者均为 20-48 岁的男性,95.70% 为男男性行为者(MSM),48.39% 为 HIV 阳性。少数病例已婚(与女性)或与子女同住。几乎所有病例都出现皮疹(98.91%),最常见的部位是生殖器和肛周(70.33%)。亲密的性接触被怀疑是主要的感染途径,中位潜伏期为 8.5 天(IQR 5.0-11.8)。病例数量增长迅速,大多数患者无国际旅行史,这表明广东省男男性行为者人群中存在持续的社区传播。此外,93.55%的病例由医疗机构发现,其中半数以上的患者在被诊断为麻痘病例前曾两次或两次以上到医院就诊,这表明临床医生需要进一步培训以提高对麻痘的敏感性。有针对性的干预措施应优先考虑男男性行为者,同时警惕向妇女和儿童等其他人群传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiology and characteristics of identified early mpox cases in Guangdong Province, China: Implications for prevention and control

In June 2023, the 2022 global mpox (monkeypox) outbreak began to affect Guangdong Province, one of the first regions in mainland China to report mpox cases. By July 10, 2023, 93 mpox cases had been reported in Guangdong Province. This study describes the epidemiological characteristics of these patients by collecting and analyzing data on demographics, sexual behavior, medical history, travel history, clinical symptoms, and diagnostic pathways and processes. The 93 mpox cases were all men aged 20-48 years, 95.70 % were men who have sex with men (MSM), and 48.39 % were HIV-positive. A few cases were married (to women) or living with children. The rash was present in almost all cases (98.91 %), with the most common sites being the genital and perianal areas (70.33 %). Intimate sexual contact was suspected to be the main route of infection, with a median incubation period of 8.5 days (IQR 5.0–11.8). The number of cases increased rapidly, and most patients had no history of international travel, suggesting sustained community transmission within the MSM population in Guangdong Province. In addition, 93.55 % of cases were detected by medical institutions, and more than half of these patients had two or more hospital visits before being diagnosed as an mpox case, indicating that clinicians need further training to increase their sensitivity to mpox. Targeted interventions should prioritize MSM while remaining vigilant for transmission to other populations, such as women and children.

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来源期刊
Biosafety and Health
Biosafety and Health Medicine-Infectious Diseases
CiteScore
7.60
自引率
0.00%
发文量
116
审稿时长
66 days
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