罕见的类风湿关节炎并发完全性心脏传导阻滞及导联血栓1例

Souilk Houda, Bouamoud Asmae, Raissouni Rim, Pr Zarzur Jamila, Pr Cherti Mohamed
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引用次数: 0

摘要

类风湿性关节炎是一种慢性炎症性自身免疫性疾病,其特征是进行性和致残性对称性多关节炎和其他器官损害。心脏表现包括心肌、瓣膜和传导组织异常。完全性心脏传导阻滞是罕见的,是由肉芽肿直接累及传导系统和随后的纤维化或炎症过程的延伸引起的。当出现症状时,通常表现为血脂降低或晕厥。在这种情况下,治疗的选择是永久性心脏起搏器植入,这可能会导致血栓形成。讨论了几个假设:心力衰竭、心房颤动、凝血功能障碍和起搏器导联本身可能易致血栓形成。在诊断出心脏装置导联上有血栓后,目前尚无确定治疗过程的标准指南。一些研究人员建议,决定应该取决于血栓的大小和患者表现出的体征和症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Rheumatoid Arthritis Complicated by Complete Heart Block and Lead Thrombosis
Rhematoid arthritis is a chronic inflammatory autoimmune disease characterized by progressive and disabling symmetrical polyarthritis and other organ damage. Heart manifestations include myocardial , valvular and conduction tissue abnormalities. Complete heart block is rare and results from a direct involvement of the conducting system with granulomas and subsequent fibrosis or extension of the inflammatory process. When symptomatic , it usually presents with lipothimia or syncope. In which case, the treatment of choice is a permanent pacemaker implantation that may complicate with thrombosis. Several hypotheses have been discussed : heart failure, atrial fibrillation, coagulopathie and the pacemaker lead itself may predispose to thrombosis. There are no established standard guidelines for determining the therapeutic course of action following the diagnosis of a clot attached to the cardiac device lead. Some researchers suggest that the decision should depend on the clot's size and the signs and symptoms exhibited by the patients.
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