新型脂质纳米给药技术综述

IF 3.1 Q2 PHARMACOLOGY & PHARMACY

Advanced pharmaceutical bulletin Pub Date : 2023-10-14 DOI:10.34172/apb.2024.012

Sonam Suresh Godase, Nilesh Shrikant Kulkarni, Shashikant Nivrutti Dhole

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引用次数: 0

摘要

新型给药系统为纳米/微制剂策略打开了大门，以克服与低溶性和渗透性药物相关的挑战。脂基纳米颗粒被广泛接受，包括脂质体、乳质体和胶束，这些都是FDA批准的。这种基于脂质的药物传递允许天然植物成分的传递，BCS II类和IV类药物的有效传递提高了其溶解度、渗透性和生物利用度。本文就脂质剂型在提高治疗效果方面的研究进展及应用作一综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A comprehensive review on Novel Lipid- Based nano drug delivery

Novel drug delivery system opens the doors towards Nano/Micro formulation strategies to overcome the challenges associated with the poorly soluble and permeable drugs. Lipid based nanoparticles are widely accepted that includes liposomes, niosomes and micelles which are FDA approved. Such lipid based drug delivery allows delivery for natural phytoconstituents, BCS class II and class IV drugs are effectively delivered to improve its solubility, permeability and bioavailability. The article provides the recent advances and application of lipid based dosage form for improvement of therapeutic efficacy.

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来源期刊

Advanced pharmaceutical bulletin PHARMACOLOGY & PHARMACY-

CiteScore

6.80

自引率

2.80%

发文量

审稿时长

12 weeks