炎症性皮肤病的临床皮肤镜研究:一项基于医院的横断面研究

Deeptara Pathak Thapa, Sushmita Pradhan, Harihar Adhikari, Sajana Bhandari, Prabhat Paudel
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摘要

皮肤镜检查是一种无创、快速、可靠的诊断技术,用于放大和可视化肉眼难以观察的皮肤表面和皮肤表面下的结构,在宏观临床皮肤病学和微观皮肤病理学之间建立了联系。本研究的目的是根据现有的文献资料,评估和比较具有相似临床表现的常见皮肤炎症性皮肤病的皮肤镜特征。所有皮肤镜检查结果均采用手持式口袋皮肤镜(Dermlite DL1)进行高倍放大。用于皮肤镜评估的变量分为血管和非血管特征以及特定线索。适当时使用描述性分析和卡方检验,p <0.05认为有统计学意义。共有205名患者参加了这项研究。最常见的临床诊断为银屑病(42.0%)、扁平苔藓(13.0%)、接触性皮炎(12.0%)、多形性轻疹(7.0%)、脂溢性皮炎(4.0%)、盘状红斑狼疮(5.0%)、玫瑰糠疹(5.0%)、荨麻疹(5.0%)和其他(7.0%)。皮肤镜下血管变化52.0%为正常,46.0%为不规则。最常见的血管类型为点状(70.0%)、线状(7.0%)和盘状(2.0%)。非血管病变占61.0%。最常见的鳞片类型为白色鳞片,占63.0%。色素改变占19.0%。在大多数炎性疾病中,最常见的血管类型为点状血管(p值0.000)。wickham条纹等特征是扁平地衣的特征(p值0.000)。各种炎症性疾病在皮镜下特有的皮镜特征,在门诊简便易行,无需任何侵入性方法,也有助于指导患者的随访管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinico-dermoscopic study of inflammatory dermatoses: a hospital based cross sectional study
Dermoscopy is a noninvasive, fast, and reliable diagnostic technique used to magnify and visualize structures on and beneath the skin surface which is difficult to observe by naked eyes, creating a link between macroscopic clinical dermatology and microscopic dermatopathology. The purpose of this study is to evaluate and compare the dermoscopic features of common inflammatory dermatological conditions of skin sharing similar clinical presentation according to the available literature data. All dermoscopic findings were studied using a handheld pocket dermoscopy (Dermlite DL1) with high magnification. Variables used for dermoscopic evaluation were divided into vascular and nonvascular features and specific clues. Descriptive analysis and Chi square test were used where appropriate and p < 0.05 was considered statistically significant. There were a total of 205 patients enrolled in the study. The most common clinical diagnosis was psoriasis seen in 42.0%, lichen planus in 13.0%, contact dermatitis in 12.0%, polymorphic light eruption 7.0%, seborrheic dermatitis 4.0%, discoid lupus erythematosus 5.0%, pityriasia Rosea 5.0%, urticaria 5.0% and others 7.0%. Dermoscopic vascular changes were seen as regular in 52.0% and irregular in 46.0%. The most common type of vessels observed were dotted in 70.0%, linear in 7.0%, and coiled in 2.0%. Non-vascular changes were seen in 61.0%. The commonest type of scales were whitish scales seen in 63.0%. Pigmentary changes were seen in 19.0%. The commonest type of vessels observed were dotted vessels (p value 0.000) in most inflammatory diseases. Features like wickham striae were characteristic of lichen planus (p value 0.000). The characteristic dermoscopic features of various inflammatory disorders with the help of a dermoscope is easy to perform in outpatient without any invasive method and also helpful in guiding management of the patients with follow-up.
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