炔雌醇与醋酸氯麦迪农合用对性的影响

L. Yu. Karakhalis, A. A. Khalafyan, G. A. Penzhoyan
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引用次数: 0

摘要

在妇产科医生可用的各种现代激素避孕方法中,首选包括孕激素的避孕方法,它不仅可以减少雄激素性皮肤病的临床表现,还可以增加性功能,至少不会对其产生负面影响。这种复方口服避孕药包括Belara,含有2mg醋酸氯麦地那酮和0.03mg炔雌醇。先前的研究评估了这种药物的安全性和阻止雄激素性皮肤病的能力,因此选择这种药物是合理的。同时,在这些研究中并没有考虑到对性功能的影响。本研究的目的是测定醋酸氯麦地那酮2mg与雌二醇0.03mg联合口服避孕药对性功能的影响。材料和方法。研究人员对68名服用复方口服避孕药的患者进行了调查,这些患者服用的复方口服避孕药含有2mg醋酸氯麦地那酮和0.03mg雌二醇(Belara),每天服用一片,连续服用21天,然后休息7天。对女性性功能指数(FSFI)进行动态调查。统计数据处理由STATISTICA 13.3 (Tibco, USA)进行。结果。对性健康产生了积极影响,包括改善了女性性功能指数的所有指标。结论。含醋酸氯麦地那酮2mg、炔雌醇0.03mg的复方口服避孕药可作为性功能减退患者的首选药物,也可在服用其他避孕药具的同时推荐服用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of the combination of ethinyl oestradiol and chlormadinon acetate on sexuality
From the variety of modern methods of hormonal contraception available in the arsenal of the obstetrician-gynecologist, preference is given to those that include gestagen, which not only reduces the clinical manifestations of androgenous dermopathy, but also increases sexual function, at least not affecting it negatively. Such combined oral contraceptives include Belara, containing chlormadinone acetate 2mg, and ethinyl oestradiol 0.03mg. The choice of this drug is justified by previous studies, which evaluated its safety and ability to stop androgenous dermopathy. At the same time, the impact on sexual function was not taken into account in these studies. The purpose of the study was to determine the effect of combined oral contraceptive containing chlormadinone acetate 2mg, and ethinyl oestradiol 0.03mg on sexual function. Material and methods . There were examined 68 patients who were prescribed a combined oral contraceptive containing chlormadinone acetate 2mg, and ethinyl oestradiol 0.03mg (Belara) – one tablet for 21 days daily, followed by a seven-day break. The female sexual function index (FSFI) was investigated in dynamics. Statistical data processing was carried out by STATISTICA 13.3 (Tibco, USA). Results . There were registered the positive effects on sexual health, which consisted in improving all indicators of female sexual function index. Conclusion . The combined oral contraceptive containing chlormadinone acetate 2mg, and ethinyl oestradiol 0.03mg may be recommended to patients with reduced sexual function as a drug of choice, as well as when reducing sexual function on the taking other contraceptives.
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